| UniProt/SwissProt ID: | NDUB2_HUMAN |
| Description: | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa [Source:HGNC Symbol;Acc:7697] |
| Location: | chr7 q34 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T25 | SGCARtAGDGG | PhosphoSitePlus | |
| Dephosphorylation site |
| NDUB2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000419357 | *106C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000247866 | R43W | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000419087 | *106C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000247866 | *106C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000247866 | I99V | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| NDUB2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NDUB2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | NDUB2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| NDUB2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0022904 | respiratory electron transport chain | TAS | biological_process |
| GO:0006120 | mitochondrial electron transport, NADH to ubiquino | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | molecular_function |
| GO:0005743 | mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | mitochondrial respiratory chain complex I | IEA | cellular_component |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0005739 | mitochondrion | IEA | cellular_component |