Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NDKB_HUMAN
Description:NME/NM23 nucleoside diphosphate kinase 2 [Source:HGNC Symbol;Acc:7850]
Location:chr17 q21.33
Node attribute:substrate; kinase; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T94VMLGEtNPADSphosphoELM
S237IHGSDsVKSAEHPRD
H118GRNIIhGSDSVNME2HPRD
S99TNPADsKPGTINDKPhosphoSitePlus
Y142EELVDyKSCAHPhosphoSitePlus
S44KFLRAsEEHLKNDKPhosphoSitePlus
Y151AHDWVyE____PhosphoSitePlus
S120NIIHGsDSVKSHPRD
H233GRNIIhGSDSVNME2HPRD
S44KFLRAsEEHLKphosphoELM
S120NIIHGsDSVKSNDKPhosphoSitePlus
S131AEKEIsLWFKPNDKPhosphoSitePlus
S122IHGSDsVKSAENDKPhosphoSitePlus
T94VMLGEtNPADSNDKPhosphoSitePlus
Y52HLKQHyIDLKDNDKPhosphoSitePlus
S159KFLRAsEEHLKNME2HPRD
S44KFLRAsEEHLKNME2HPRD
H118GRNIIhGSDSVNDKPhosphoSitePlus
S235NIIHGsDSVKSHPRD
S122IHGSDsVKSAEHPRD

Dephosphorylation site
NDKB_HUMAN do not have dephosphorylation site.

Mutation site
NDKB_HUMAN do not have mutation site.

Differential expressed protein
NDKB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NDKB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NDKB_HUMANNDKB_HUMANkinase -> substrateHPRD
NDKB_HUMANMYC_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa01100Metabolic pathways
hsa00230Purine metabolism
hsa01100Metabolic pathways
hsa00240Pyrimidine metabolism
hsa00230Purine metabolism
hsa00240Pyrimidine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006228UTP biosynthetic processIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0009142nucleoside triphosphate biosynthetic processIDAbiological_process
GO:0006241CTP biosynthetic processIEAbiological_process
GO:0006183GTP biosynthetic processIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0007155cell adhesionTASbiological_process
GO:0004550nucleoside diphosphate kinase activityIEAmolecular_function
GO:0005634nucleusNAScellular_component
GO:0005829cytosolTAScellular_component
GO:0030027lamellipodiumIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0004673protein histidine kinase activityIEAmolecular_function
GO:0045682regulation of epidermis developmentIMPbiological_process
GO:0015949nucleobase-containing small molecule interconversiTASbiological_process
GO:0043066negative regulation of apoptotic processIMPbiological_process
GO:0045618positive regulation of keratinocyte differentiatioIMPbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0055086nucleobase-containing small molecule metabolic proTASbiological_process
GO:0050679positive regulation of epithelial cell proliferatiIMPbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0001726ruffleIDAcellular_component
GO:0006165nucleoside diphosphate phosphorylationIEAbiological_process


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