| UniProt/SwissProt ID: | NDF4_HUMAN |
| Description: | neuronal differentiation 4 [Source:HGNC Symbol;Acc:13802] |
| Location: | chr12 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S198 | CDSAIsVHNFN | PhosphoSitePlus | |
| Dephosphorylation site |
| NDF4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000242994 | Q205H | BIOMART | Gastric Cancer | 21930507, 21930502 |
| ENSP00000242994 | K74* | COSMIC | Ovarian Cancer | 21720365 |
| ENSP00000242994 | W137L | COSMIC | Melanoma | 21499247 |
| ENSP00000242994 | N134D | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 |
| ENSP00000242994 | P178S | COSMIC | Skin Cancer | 21984974 |
| ENSP00000242994 | G320V | TCGA | Ovarian Cancer | 21720365, 18772890 |
| ENSP00000242994 | G320V | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| NDF4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NDF4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ST17A_HUMAN | NDF4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| NDF4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0060041 | retina development in camera-type eye | IEA | biological_process |
| GO:0046983 | protein dimerization activity | IEA | molecular_function |
| GO:0001764 | neuron migration | IEA | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0043010 | camera-type eye development | IEA | biological_process |
| GO:0045165 | cell fate commitment | IEA | biological_process |
| GO:0045597 | positive regulation of cell differentiation | IEA | biological_process |
| GO:0045597 | positive regulation of cell differentiation | ISS | biological_process |
| GO:0035881 | amacrine cell differentiation | ISS | biological_process |
| GO:0007219 | Notch signaling pathway | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0035881 | amacrine cell differentiation | IEA | biological_process |
| GO:0007405 | neuroblast proliferation | IEA | biological_process |
| GO:0048666 | neuron development | IEA | biological_process |
| GO:0010001 | glial cell differentiation | IEA | biological_process |