Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NASP_HUMAN
Description:nuclear autoantigenic sperm protein (histone-binding) [Source:HGNC Symbol;Acc:7644]
Location:chr1 p34.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S480EETEGsEEDDKPhosphoSitePlus; HPRD; phosphoELM
S141DETEGsEEDDKHPRD
S210WLTETsEEAKGPhosphoSitePlus; HPRD
S567VEEFQsCLNLQSHNi-TPRPhosphoSitePlus
S659EDAKEsQRSGNPhosphoSitePlus
T683STSGFtPGGGGPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S350PGGGGsSVSMIHPRD
S30PAPSTsADKVEHPRD
T344STSGFtPGGGGHPRD
T448VAQGAtEKSPEHPRD
S432LSVEEsEAAGDHPRD; phosphoELM
S497EMPNDsVLENKPhosphoSitePlus; HPRD; phosphoELM
T534FKRQEtKEAQLPhosphoSitePlus
T248KSVSGtDVQEEHPRD
S244AEEEKsVSGTDPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S41SLDVDsEAKKLPhosphoSitePlus
T170LAKPEtDKEQDPhosphoSitePlus
S164VLENKsLQENEHPRD
Y148LREQVyDAMGEPhosphoSitePlus
S127KTEDEsLVENNPhosphoSitePlus; HPRD
T123EEGEKtEDESLPhosphoSitePlus; HPRD; SysPTM
T138DNIDEtEGSEEHPRD
S503VLENKsLQENEPhosphoSitePlus; HPRD
S164KTEDKsLAKPEHPRD
T151KENDKtEEMPNHPRD
Y575NLQEQyLEAHDSHNi-TPRPhosphoSitePlus
T425PSQEEtKLSVEPhosphoSitePlus; HPRD; phosphoELM
T477KEGEEtEGSEEPhosphoSitePlus; HPRD; phosphoELM
S191MDISKsAEEPQPhosphoSitePlus
T228NEAEVtSGKPEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S28DVPAPsTSADKPhosphoSitePlus
T464AANEEtQEREEPhosphoSitePlus; HPRD; phosphoELM
T490KENDKtEEMPNPhosphoSitePlus; HPRD
S176DKEQDsEMEKGPhosphoSitePlus
S384AVNGPsVVGDQPhosphoSitePlus
S321EKVVTsENEAGPhosphoSitePlus
S189EDMDIsKSAEEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T396PIEPQtSIERLPhosphoSitePlus
S387KPEEEsPRKDDHPRD
S246EEKSVsGTDVQPhosphoSitePlus; HPRD
S299EVEAEsLDPTVPhosphoSitePlus
S428EETKLsVEESEPhosphoSitePlus; HPRD; phosphoELM
S689PGGGGsSVSMIHPRD; phosphoELM
S421AKLVPsQEETKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S397IEPQTsIERLTPhosphoSitePlus
S598AYGYNsQYDEATPR_1PhosphoSitePlus
T390VVGDQtPIEPQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S751GDAVPsGNEVSPhosphoSitePlus
S158EMPNDsVLENKHPRD
S696VSMIAsRKPTDPhosphoSitePlus
S451GATEKsPEDKVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T700ASRKPtDGASSPhosphoSitePlus
S36ADKVEsLDVDSPhosphoSitePlus
S726KPEEEsPRKDDPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S408ETKDGsGLEEKPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
NASP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384529N744IBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000255120Gastric CancerMetastasiscell lineUp1.517022644
ENSP00000255120Gastric CancerMetastasiscell lineUp1.517022644

Hyperphosphorylation site
NASP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6A4_HUMANNASP_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANNASP_HUMANkinase -> substrateRobert H Newman (2013)
KPCZ_HUMANNASP_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
NASP_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0015031protein transportIEAbiological_process
GO:0051879Hsp90 protein bindingISSmolecular_function
GO:0005634nucleusISScellular_component
GO:0006260DNA replicationISSbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0043486histone exchangeISSbiological_process
GO:0008283cell proliferationISSbiological_process
GO:0042393histone bindingIEAmolecular_function
GO:0007049cell cycleISSbiological_process
GO:0001824blastocyst developmentISSbiological_process
GO:0005634nucleusIEAcellular_component