Phosphorylation

Protein information

UniProt/SwissProt ID:	NACC2_HUMAN
Description:	NACC family member 2, BEN and BTB (POZ) domain containing [Source:HGNC Symbol;Acc:23846]
Location:	chr9 q34.3
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
T388	FFDRNtLANSC	BEN	PhosphoSitePlus
T505	RGDAAtIVALR		PhosphoSitePlus
Y29	RLLGLyCDVSI	BTB	PhosphoSitePlus
Y224	PRVSYyGVPSL		PhosphoSitePlus
S323	VALPAsLISQI		PhosphoSitePlus
S33	LYCDVsIVVKG	BTB	PhosphoSitePlus
Y223	LPRVSyYGVPS		PhosphoSitePlus
S228	YYGVPsLATLI		PhosphoSitePlus

NACC2_HUMAN do not have dephosphorylation site.

NACC2_HUMAN do not have mutation site.

NACC2_HUMAN is not differential expressed protein.

NACC2_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
PKN1_HUMAN	NACC2_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

NACC2_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0016575	histone deacetylation	IDA	biological_process
GO:0045892	negative regulation of transcription, DNA-dependen	ISS	biological_process
GO:0004407	histone deacetylase activity	IDA	molecular_function
GO:0000978	RNA polymerase II core promoter proximal region se	IDA	molecular_function
GO:0000790	nuclear chromatin	IDA	cellular_component
GO:0016581	NuRD complex	IDA	cellular_component
GO:0034629	cellular protein complex localization	IDA	biological_process
GO:0051260	protein homooligomerization	ISS	biological_process
GO:0006366	transcription from RNA polymerase II promoter	IDA	biological_process
GO:1900477	negative regulation of G1/S transition of mitotic	IDA	biological_process
GO:0042826	histone deacetylase binding	IPI	molecular_function
GO:0001078	RNA polymerase II core promoter proximal region se	IDA	molecular_function
GO:0001076	RNA polymerase II transcription factor binding tra	IDA	molecular_function
GO:0008630	intrinsic apoptotic signaling pathway in response	IDA	biological_process
GO:0010608	posttranscriptional regulation of gene expression	IMP	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0042803	protein homodimerization activity	IDA	molecular_function
GO:0016604	nuclear body	ISS	cellular_component
GO:0005634	nucleus	ISS	cellular_component
GO:0008284	positive regulation of cell proliferation	ISS	biological_process
GO:0008285	negative regulation of cell proliferation	IDA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network