Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MYEF2_HUMAN
Description:myelin expression factor 2 [Source:HGNC Symbol;Acc:17940]
Location:chr15 q21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T234GRLGStIFVANPhosphoSitePlus
Y164ETMNKyDLSGRRRM_1PhosphoSitePlus
S431QGFGDsFGRLGPhosphoSitePlus
Y317VPHEEyRSHDGPhosphoSitePlus
S233AGRLGsTIFVAPhosphoSitePlus
S17ATGGDsPHLQPPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
MYEF2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000316950M413ICOSMICHead and Neck Cancer21798893
ENSP00000316950G433CCOSMICLung Cancer20668451
ENSP00000316950D165HCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000316950Pancreatic CancerNormal vs. CancertissueUp2.619199705

Hyperphosphorylation site
MYEF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FRK_HUMANMYEF2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MYEF2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000166nucleotide bindingIEAmolecular_function
GO:0030182neuron differentiationIEPbiological_process
GO:0014902myotube differentiationIEPbiological_process
GO:0005634nucleusIDAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component


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