Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MYCD_HUMAN
Description:myocardin [Source:HGNC Symbol;Acc:16067]
Location:chr17 p12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T732VKQQMtRSQQMPhosphoSitePlus
S242AVKSKsLGDSKPhosphoSitePlus
S734QQMTRsQQMDEPhosphoSitePlus
S459SSPPIsPASSDGSK3BHPRD
S451FYHFGsTSSSPGSK3BHPRD
S455GSTSSsPPISPGSK3BHPRD
S229GLGPPsTPIAVPhosphoSitePlus
T230LGPPStPIAVHPhosphoSitePlus
S630SSTFLsPQCSPGSK3BHPRD
S704KFSIPsPTFSKPhosphoSitePlus
S626TNVLSsTFLSPGSK3BHPRD
S634LSPQCsPQHSPGSK3BHPRD

Dephosphorylation site
MYCD_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000341835T493MCOSMICHead and Neck Cancer21798893
ENSP00000341835S185LCOSMICOvarian Cancer21720365
ENSP00000401678S185LTCGAOvarian Cancer21720365, 18772890
ENSP00000341835E325KCOSMICMelanoma21499247
ENSP00000379311*685SCOSMICBreast Cancer16959974
ENSP00000341835G610RCOSMICMelanoma21499247

Differential expressed protein
MYCD_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MYCD_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GSK3B_HUMANMYCD_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
MYCD_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060065uterus developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0001046core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0071456cellular response to hypoxiaIEAbiological_process
GO:2000721positive regulation of transcription from RNA polyIDAbiological_process
GO:0010667negative regulation of cardiac muscle cell apoptotIEAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045987positive regulation of smooth muscle contractionIDAbiological_process
GO:0003257positive regulation of transcription from RNA polyIDAbiological_process
GO:1900222negative regulation of beta-amyloid clearanceIMPbiological_process
GO:0042692muscle cell differentiationIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0045736negative regulation of cyclin-dependent protein kiIDAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0048286lung alveolus developmentIEAbiological_process
GO:0051091positive regulation of sequence-specific DNA bindiIDAbiological_process
GO:0035051cardiocyte differentiationNASbiological_process
GO:0035065regulation of histone acetylationIEAbiological_process
GO:0006366transcription from RNA polymerase II promoterIEAbiological_process
GO:0030511positive regulation of transforming growth factor IEAbiological_process
GO:0051145smooth muscle cell differentiationIEAbiological_process
GO:0051145smooth muscle cell differentiationIMPbiological_process
GO:0097070ductus arteriosus closureIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0035065regulation of histone acetylationISSbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0001076RNA polymerase II transcription factor binding traISSmolecular_function
GO:0001560regulation of cell growth by extracellular stimuluIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0071363cellular response to growth factor stimulusIEAbiological_process
GO:0055007cardiac muscle cell differentiationIEAbiological_process
GO:0051152positive regulation of smooth muscle cell differenIDAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function
GO:2000721positive regulation of transcription from RNA polyIEAbiological_process
GO:0070412R-SMAD bindingIEAmolecular_function
GO:2000724positive regulation of cardiac vascular smooth musISSbiological_process
GO:0019904protein domain specific bindingIDAmolecular_function
GO:0060157urinary bladder developmentIEAbiological_process
GO:0042826histone deacetylase bindingIEAmolecular_function
GO:0043388positive regulation of DNA bindingIEAbiological_process
GO:0055012ventricular cardiac muscle cell differentiationIEAbiological_process
GO:0051150regulation of smooth muscle cell differentiationIEAbiological_process
GO:0010832negative regulation of myotube differentiationIEAbiological_process
GO:0003231cardiac ventricle developmentIEAbiological_process
GO:0001076RNA polymerase II transcription factor binding traIEAmolecular_function
GO:0008285negative regulation of cell proliferationIDAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:2000724positive regulation of cardiac vascular smooth musIEAbiological_process
GO:0048565digestive tract developmentIEAbiological_process
GO:0051150regulation of smooth muscle cell differentiationTASbiological_process
GO:0045661regulation of myoblast differentiationIEAbiological_process
GO:0001570vasculogenesisIEAbiological_process
GO:0001666response to hypoxiaIEPbiological_process
GO:0035035histone acetyltransferase bindingIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0035733hepatic stellate cell activationIEAbiological_process
GO:2001015negative regulation of skeletal muscle cell differIDAbiological_process
GO:2000727positive regulation of cardiac muscle cell differeIDAbiological_process
GO:0003713transcription coactivator activityIEAmolecular_function
GO:0055007cardiac muscle cell differentiationISSbiological_process
GO:0061049cell growth involved in cardiac muscle cell develoIEAbiological_process