| UniProt/SwissProt ID: | MTF2_HUMAN |
| Description: | metal response element binding transcription factor 2 [Source:HGNC Symbol;Acc:29535] |
| Location: | chr1 p22.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y245 | FGDRFyTFICS | PHD | PhosphoSitePlus |
| S27 | QKTPTsLTKLS | PhosphoSitePlus; HPRD; phosphoELM | |
| Y327 | EALNDyKTMFM | PhosphoSitePlus | |
| T29 | TPTSLtKLSLQ | PhosphoSitePlus | |
| T24 | RRNQKtPTSLT | PhosphoSitePlus; HPRD; phosphoELM | |
| S452 | HSSNTsDVDFT | PhosphoSitePlus | |
| S488 | TRTGRsWPAAI | PhosphoSitePlus; HPRD; phosphoELM | |
| Dephosphorylation site |
| MTF2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000444962 | V414L | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000443295 | V414L | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| MTF2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MTF2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK08_HUMAN | MTF2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| MTF2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |