| UniProt/SwissProt ID: | MRGX2_HUMAN |
| Description: | MAS-related GPR, member X2 [Source:HGNC Symbol;Acc:17983] |
| Location: | chr11 p15.1 |
| Node attribute: | receptor |
| Phosphorylation site |
| MRGX2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| MRGX2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000333800 | R141H | COSMIC | Hepatocellular Carcinoma | 21822264 |
| Differential expressed protein |
| MRGX2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MRGX2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CORT_HUMAN | MRGX2_HUMAN | ligand -> receptor | HPMR |
| ADML_HUMAN | MRGX2_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| MRGX2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042923 | neuropeptide binding | IPI | molecular_function |
| GO:0016021 | integral to membrane | IC | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0030431 | sleep | NAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IDA | molecular_function |
| GO:0019233 | sensory perception of pain | NAS | biological_process |