Phosphorylation

Protein information

UniProt/SwissProt ID:	MMP9_HUMAN
Description:	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) [Source:HGNC Symbol;Acc:7176]
Location:	chr20 q13.12
Node attribute:	ligand

Position	PhosphoPeptide	Catalytic kinase	Source
Y241	FEGRSySACTT	Peptidase_M10; fn2	PhosphoSitePlus
S628	KMLLFsGRRLW	Hemopexin	PhosphoSitePlus

MMP9_HUMAN do not have dephosphorylation site.

MMP9_HUMAN do not have mutation site.

Ensembl ID	Cancer name	Design	Sample	Change	Ratio	Pubmed
ENSP00000361405	Pancreatic Cancer	Normal vs. Cancer	tissue	Down	0.05	16215274
ENSP00000361405	Leukemia	Normal vs. Cancer	tissue	Down		15501966

MMP9_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
MMP9_HUMAN	LRP1_HUMAN	ligand -> receptor	HPMR

KEGG Pathway

KEGG ID	Pathway
hsa05202	Transcriptional misregulation in cancer
hsa05219	Bladder cancer
hsa05200	Pathways in cancer
hsa04670	Leukocyte transendothelial migration

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0051549	positive regulation of keratinocyte migration	IMP	biological_process
GO:0001501	skeletal system development	IEA	biological_process
GO:0030225	macrophage differentiation	TAS	biological_process
GO:0030574	collagen catabolic process	IEA	biological_process
GO:0022617	extracellular matrix disassembly	TAS	biological_process
GO:0008270	zinc ion binding	TAS	molecular_function
GO:0030198	extracellular matrix organization	IEA	biological_process
GO:0005518	collagen binding	TAS	molecular_function
GO:0007566	embryo implantation	IEA	biological_process
GO:0005615	extracellular space	IDA	cellular_component
GO:0008237	metallopeptidase activity	IEA	molecular_function
GO:0005576	extracellular region	TAS	cellular_component
GO:0006508	proteolysis	IDA	biological_process
GO:0005578	proteinaceous extracellular matrix	IEA	cellular_component
GO:0008233	peptidase activity	IEA	molecular_function
GO:0005515	protein binding	IPI	molecular_function
GO:0043065	positive regulation of apoptotic process	IEA	biological_process
GO:0030198	extracellular matrix organization	TAS	biological_process
GO:0004222	metalloendopeptidase activity	IDA	molecular_function
GO:0031012	extracellular matrix	IEA	cellular_component
GO:0004222	metalloendopeptidase activity	IEA	molecular_function

Human Phosphorylation Mediated
Signaling Transduction Network