Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MMP9_HUMAN
Description:matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) [Source:HGNC Symbol;Acc:7176]
Location:chr20 q13.12
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y241FEGRSySACTTPeptidase_M10; fn2PhosphoSitePlus
S628KMLLFsGRRLWHemopexinPhosphoSitePlus

Dephosphorylation site
MMP9_HUMAN do not have dephosphorylation site.

Mutation site
MMP9_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000361405Pancreatic CancerNormal vs. CancertissueDown0.0516215274
ENSP00000361405LeukemiaNormal vs. CancertissueDown15501966

Hyperphosphorylation site
MMP9_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MMP9_HUMANLRP1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05202Transcriptional misregulation in cancer
hsa05219Bladder cancer
hsa05200Pathways in cancer
hsa04670Leukocyte transendothelial migration

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051549positive regulation of keratinocyte migrationIMPbiological_process
GO:0001501skeletal system developmentIEAbiological_process
GO:0030225macrophage differentiationTASbiological_process
GO:0030574collagen catabolic processIEAbiological_process
GO:0022617extracellular matrix disassemblyTASbiological_process
GO:0008270zinc ion bindingTASmolecular_function
GO:0030198extracellular matrix organizationIEAbiological_process
GO:0005518collagen bindingTASmolecular_function
GO:0007566embryo implantationIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0008237metallopeptidase activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0006508proteolysisIDAbiological_process
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0008233peptidase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0030198extracellular matrix organizationTASbiological_process
GO:0004222metalloendopeptidase activityIDAmolecular_function
GO:0031012extracellular matrixIEAcellular_component
GO:0004222metalloendopeptidase activityIEAmolecular_function


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23