Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MMP7_HUMAN
Description:matrix metallopeptidase 7 (matrilysin, uterine) [Source:HGNC Symbol;Acc:7174]
Location:chr11 q22.2
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S47FYLYDsETKNAPG_binding_1PhosphoSitePlus
T49LYDSEtKNANSPG_binding_1PhosphoSitePlus

Dephosphorylation site
MMP7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000260227V114ICOSMICHead and Neck Cancer21798893
ENSP00000260227L6MCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000260227Uterine CancerNormal vs. Cancercell lineUp190015838902
ENSP00000260227Pancreatic CancerNormal vs. CancertissueUp1.619199705

Hyperphosphorylation site
MMP7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LEF1_HUMANMMP7_HUMANTF -> target geneKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04310Wnt signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050829defense response to Gram-negative bacteriumIEAbiological_process
GO:0005615extracellular spaceTAScellular_component
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0030198extracellular matrix organizationTASbiological_process
GO:0031012extracellular matrixIEAcellular_component
GO:0042742defense response to bacteriumIEAbiological_process
GO:0004222metalloendopeptidase activityIEAmolecular_function
GO:0030574collagen catabolic processIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0008237metallopeptidase activityIEAmolecular_function
GO:0022617extracellular matrix disassemblyTASbiological_process
GO:0002779antibacterial peptide secretionIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0042127regulation of cell proliferationIEAbiological_process
GO:0006508proteolysisIEAbiological_process
GO:0050830defense response to Gram-positive bacteriumIEAbiological_process


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