Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MMP13_HUMAN
Description:matrix metallopeptidase 13 (collagenase 3) [Source:HGNC Symbol;Acc:7159]
Location:chrHG305_PATCH q22.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y366DILEGyPKKISHemopexinPhosphoSitePlus
Y360WALNGyDILEGHemopexinPhosphoSitePlus

Dephosphorylation site
MMP13_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000260302D30NCOSMICOvarian Cancer21720365
ENSP00000260302V462ICOSMICOvarian Cancer21720365
ENSP00000260302D100NCOSMICMelanoma21499247

Differential expressed protein
MMP13_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MMP13_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MMP13_HUMANLRP1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
MMP13_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051216cartilage developmentIEAbiological_process
GO:0022617extracellular matrix disassemblyTASbiological_process
GO:0044267cellular protein metabolic processIEAbiological_process
GO:0030574collagen catabolic processIEAbiological_process
GO:0008237metallopeptidase activityIEAmolecular_function
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0005615extracellular spaceTAScellular_component
GO:0004222metalloendopeptidase activityIEAmolecular_function
GO:0030198extracellular matrix organizationTASbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005509calcium ion bindingIEAmolecular_function
GO:0031012extracellular matrixIEAcellular_component
GO:0008233peptidase activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0006508proteolysisIEAbiological_process
GO:0030282bone mineralizationIEAbiological_process


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