Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MAK_HUMAN
Description:male germ cell-associated kinase [Source:HGNC Symbol;Acc:6816]
Location:chr6 p24.2
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y480TSKQYyLKQSRPhosphoSitePlus
S161YTDYVsTRWYRPkinasePhosphoSitePlus
T162TDYVStRWYRAPkinasePhosphoSitePlus
Y156RSQPPyTDYVSPkinasePhosphoSitePlus
T157SQPPYtDYVSTPkinasePhosphoSitePlus
T5MRQLHPRD
S510NPHTWsNQLFPPhosphoSitePlus
Y159PPYTDyVSTRWPkinasePhosphoSitePlus

Dephosphorylation site
MAK_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000313021R272PGreenman2007Breast Cancer17344846, 18428421
ENSP00000346484R272PGreenman2007Breast Cancer17344846, 18428421
ENSP00000313021R272PHPIbreast ductal carcinoma17344846
ENSP00000346484R272PHPIbreast ductal carcinoma17344846

Differential expressed protein
MAK_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MAK_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MAK_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MAK_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0072686mitotic spindleIDAcellular_component
GO:0006468protein phosphorylationNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005524ATP bindingNASmolecular_function
GO:0045494photoreceptor cell maintenanceIEAbiological_process
GO:0045494photoreceptor cell maintenanceISSbiological_process
GO:0001917photoreceptor inner segmentIDAcellular_component
GO:0003713transcription coactivator activityIDAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0001750photoreceptor outer segmentISScellular_component
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0001750photoreceptor outer segmentIEAcellular_component
GO:0004672protein kinase activityNASmolecular_function
GO:0007283spermatogenesisNASbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005813centrosomeIDAcellular_component
GO:0030496midbodyIDAcellular_component
GO:0004693cyclin-dependent protein kinase activityIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0046777protein autophosphorylationIMPbiological_process
GO:0030154cell differentiationIEAbiological_process


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