Phosphorylation

Protein information

UniProt/SwissProt ID:	MAK_HUMAN
Description:	male germ cell-associated kinase [Source:HGNC Symbol;Acc:6816]
Location:	chr6 p24.2
Node attribute:	kinase

Position	PhosphoPeptide	Catalytic kinase	Source
Y480	TSKQYyLKQSR		PhosphoSitePlus
S161	YTDYVsTRWYR	Pkinase	PhosphoSitePlus
T162	TDYVStRWYRA	Pkinase	PhosphoSitePlus
Y156	RSQPPyTDYVS	Pkinase	PhosphoSitePlus
T157	SQPPYtDYVST	Pkinase	PhosphoSitePlus
T5	MRQL		HPRD
S510	NPHTWsNQLFP		PhosphoSitePlus
Y159	PPYTDyVSTRW	Pkinase	PhosphoSitePlus

MAK_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000313021	R272P	Greenman2007	Breast Cancer	17344846, 18428421
ENSP00000346484	R272P	Greenman2007	Breast Cancer	17344846, 18428421
ENSP00000313021	R272P	HPI	breast ductal carcinoma	17344846
ENSP00000346484	R272P	HPI	breast ductal carcinoma	17344846

MAK_HUMAN is not differential expressed protein.

MAK_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
MAK_HUMAN	CBL_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

MAK_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0005515	protein binding	IEA	molecular_function
GO:0005634	nucleus	IDA	cellular_component
GO:0072686	mitotic spindle	IDA	cellular_component
GO:0006468	protein phosphorylation	NAS	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0005524	ATP binding	NAS	molecular_function
GO:0045494	photoreceptor cell maintenance	IEA	biological_process
GO:0045494	photoreceptor cell maintenance	ISS	biological_process
GO:0001917	photoreceptor inner segment	IDA	cellular_component
GO:0003713	transcription coactivator activity	IDA	molecular_function
GO:0006355	regulation of transcription, DNA-dependent	IEA	biological_process
GO:0016772	transferase activity, transferring phosphorus-cont	IEA	molecular_function
GO:0001750	photoreceptor outer segment	ISS	cellular_component
GO:0007275	multicellular organismal development	IEA	biological_process
GO:0001750	photoreceptor outer segment	IEA	cellular_component
GO:0004672	protein kinase activity	NAS	molecular_function
GO:0007283	spermatogenesis	NAS	biological_process
GO:0006351	transcription, DNA-dependent	IEA	biological_process
GO:0005813	centrosome	IDA	cellular_component
GO:0030496	midbody	IDA	cellular_component
GO:0004693	cyclin-dependent protein kinase activity	IEA	molecular_function
GO:0005737	cytoplasm	IEA	cellular_component
GO:0004713	protein tyrosine kinase activity	IEA	molecular_function
GO:0046777	protein autophosphorylation	IMP	biological_process
GO:0030154	cell differentiation	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network