| UniProt/SwissProt ID: | MAG_HUMAN |
| Description: | myelin associated glycoprotein [Source:HGNC Symbol;Acc:6783] |
| Location: | chr19 q13.12 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y620 | EELAEyAEIR | FYN | HPRD |
| Y571 | GAPEKyESERR | PhosphoSitePlus | |
| S441 | SNPEPsVAFEL | PhosphoSitePlus | |
| S547 | VTESPsFSAGD | PhosphoSitePlus | |
| S436 | LCVVKsNPEPS | PhosphoSitePlus | |
| T543 | RKKNVtESPSF | PhosphoSitePlus | |
| Dephosphorylation site |
| MAG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000355234 | E575K | COSMIC | Melanoma | 21499247 | ENSP00000376048 | S545R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000355234 | N492S | COSMIC | Lung Cancer | 20668451 | ENSP00000355234 | H177Y | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000355234 | T368M | COSMIC | Central Nervous System Neoplasms | 18772890 | ENSP00000355234 | S545R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000355234 | D561N | COSMIC | Skin Cancer | 21984974 | ENSP00000355234 | L202M | COSMIC | Breast Cancer | 20668451 | ENSP00000355234 | R425* | COSMIC | Head and Neck Cancer | 21984974 | ENSP00000355234 | S351R | COSMIC | Lung Cancer | 20668451 |
| Differential expressed protein |
| MAG_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MAG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FYN_HUMAN | MAG_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0033270 | paranode region of axon | IEA | cellular_component |
| GO:0048011 | nerve growth factor receptor signaling pathway | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0050900 | leukocyte migration | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0043209 | myelin sheath | IEA | cellular_component |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0043220 | Schmidt-Lanterman incisure | IEA | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0050770 | regulation of axonogenesis | TAS | biological_process |
| GO:0050771 | negative regulation of axonogenesis | TAS | biological_process |