| UniProt/SwissProt ID: | LRC4C_HUMAN |
| Description: | leucine rich repeat containing 4C [Source:HGNC Symbol;Acc:29317] |
| Location: | chr11 p12 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T324 | MAPSNtACCAR | PhosphoSitePlus | |
| S603 | YNSYKsPFNHT | PhosphoSitePlus | |
| T610 | FNHTTtVNTIN | PhosphoSitePlus | |
| S616 | VNTINsIHSSV | PhosphoSitePlus | |
| S631 | LIRMNsKDNVQ | PhosphoSitePlus | |
| Y548 | MLVIFyKMRKQ | TM | PhosphoSitePlus |
| Dephosphorylation site |
| LRC4C_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000278198 | Q87E | COSMIC | Ovarian Cancer | 21720365 | ENSP00000278198 | D483E | COSMIC | Central Nervous System Neoplasms | 18772890 | ENSP00000278198 | P580A | COSMIC | Ovarian Cancer | 21720365 | ENSP00000278198 | E211* | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000278198 | C426R | COSMIC | Skin Cancer | 21984974 | ENSP00000278198 | N208S | COSMIC | Melanoma | 21499247 | ENSP00000278198 | W315* | COSMIC | Melanoma | 21499247 | ENSP00000278198 | L595I | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| LRC4C_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LRC4C_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NTNG1_HUMAN | LRC4C_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04360 | Axon guidance |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0050770 | regulation of axonogenesis | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016020 | membrane | IDA | cellular_component |