| UniProt/SwissProt ID: | LC7L2_HUMAN |
| Description: | LUC7-like 2 (S. cerevisiae) [Source:HGNC Symbol;Acc:21608] |
| Location: | chr7 q34 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S347 | DQDLAsCDRDR | PhosphoSitePlus; HPRD; SysPTM | |
| S353 | CDRDRsSRDRS | PhosphoSitePlus; HPRD | |
| S309 | RSRSSsRSRSR | PhosphoSitePlus; HPRD | |
| S327 | SSRDRsRERSK | PhosphoSitePlus; HPRD | |
| S307 | RHRSRsSSRSR | HPRD | |
| T17 | DQLMGtSRDGD | HPRD; phosphoELM; SysPTM | |
| S285 | RSRSMsRERKR | PhosphoSitePlus; HPRD | |
| T23 | SRDGDtTRQRI | HPRD | |
| T111 | KRLAEtQEEIS | HPRD; phosphoELM | |
| S18 | QLMGTsRDGDT | LUC7 | PhosphoSitePlus; SysPTM |
| S373 | KRSYEsANGRS | PhosphoSitePlus | |
| S384 | EDRRSsEEREA | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S378 | SANGRsEDRRS | PhosphoSitePlus; HPRD | |
| S18 | QLMGTsRDGDT | HPRD; phosphoELM; SysPTM | |
| S358 | SSRDRsPRDRD | PhosphoSitePlus; HPRD; phosphoELM | |
| T17 | DQLMGtSRDGD | LUC7 | PhosphoSitePlus; SysPTM |
| S271 | KNPKRsRSREH | PhosphoSitePlus; HPRD | |
| S354 | DRDRSsRDRSP | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S305 | RHRHRsRSSSR | PhosphoSitePlus; HPRD | |
| T111 | KRLAEtQEEIS | LUC7 | PhosphoSitePlus |
| S281 | HRRHRsRSMSR | PhosphoSitePlus; HPRD | |
| S283 | RHRSRsMSRER | PhosphoSitePlus; HPRD | |
| S323 | RSRHSsRDRSR | PhosphoSitePlus; HPRD | |
| S383 | SEDRRsSEERE | PhosphoSitePlus; HPRD; phosphoELM | |
| S370 | KDKKRsYESAN | PhosphoSitePlus; HPRD | |
| S308 | HRSRSsSRSRS | HPRD | |
| S273 | PKRSRsREHRR | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| LC7L2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000263545 | E371G | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000263545 | N374D | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000347005 | N375D | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000347005 | E372G | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000347005 | P178A | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 |
| Differential expressed protein |
| LC7L2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LC7L2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PAK4_HUMAN | LC7L2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AKT1_HUMAN | LC7L2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| LC7L2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0019899 | enzyme binding | IPI | molecular_function |
| GO:0016607 | nuclear speck | IEA | cellular_component |
| GO:0046872 | metal ion binding | IEA | molecular_function |