Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LBR_HUMAN
Description:lamin B receptor [Source:HGNC Symbol;Acc:6518]
Location:chr1 q42.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S130FGNSIsRYNGEPhosphoSitePlus
S80RRGSRsRSRSRHPRD
S97KSARRsASASHPhosphoSitePlus; HPRD
S20RWPGSsLYYEVPhosphoSitePlus
S71GSTSSsPSRRRCDK1phosphoELM
Y132NSISRyNGEPEPhosphoSitePlus
Y23GSSLYyEVEILPhosphoSitePlus
T380NPRIGtFDLKYERG4_ERG24PhosphoSitePlus
S71GSTSSsPSRRRCDC2(CDK1RegPhos
S84RSRSRsRSPGRPhosphoSitePlus; HPRD
S67QRKGGsTSSSPPhosphoSitePlus
S78SRRRGsRSRSRHPRD
Y22PGSSLyYEVEIPhosphoSitePlus
Y161SQESSyIATQYPhosphoSitePlus
S86RSRSRsPGRPPPhosphoSitePlus; HPRD
S167IATQYsLRPRRPhosphoSitePlus
S160LSQESsYIATQPhosphoSitePlus
S71GSTSSsPSRRRPhosphoSitePlus
S101RSASAsHQADIPhosphoSitePlus; HPRD; SysPTM
T284KVVEGtPLIDGERG4_ERG24PhosphoSitePlus
T200RTFEVtPIRAKERG4_ERG24PhosphoSitePlus
T164SSYIAtQYSLRPhosphoSitePlus
Y166YIATQySLRPRPhosphoSitePlus
T118VEVKLtPLILKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S156EKFSLsQESSYPhosphoSitePlus
S99ARRSAsASHQAPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S128KPFGNsISRYNPhosphoSitePlus
S59IKPLTsFRQRKPhosphoSitePlus
Y385TFDLKyFCELRERG4_ERG24PhosphoSitePlus

Dephosphorylation site
LBR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000339883A94GCOSMICOvarian Cancer21720365
ENSP00000272163P515LCOSMICMelanoma21499247
ENSP00000339883F197VBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000272163A94GCOSMICOvarian Cancer21720365
ENSP00000339883P515LCOSMICMelanoma21499247
ENSP00000272163F197VBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
LBR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LBR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK1_HUMANLBR_HUMANkinase -> substrateRegPhos
ZAGL2_HUMANLBR_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
LBR_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005635nuclear envelopeIEAcellular_component
GO:0016628oxidoreductase activity, acting on the CH-CH groupIEAmolecular_function
GO:0005739mitochondrionIDAcellular_component
GO:0006695cholesterol biosynthetic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0005521lamin bindingTASmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0031965nuclear membraneIDAcellular_component
GO:0005639integral to nuclear inner membraneTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0070087chromo shadow domain bindingIPImolecular_function
GO:0016021integral to membraneIDAcellular_component


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