| UniProt/SwissProt ID: | LAMC3_HUMAN |
| Description: | laminin, gamma 3 [Source:HGNC Symbol;Acc:6494] |
| Location: | chr9 q34.12 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y160 | GPWEPyQFYSA | Laminin_N | PhosphoSitePlus |
| S151 | AIYKRsRADGP | Laminin_N | PhosphoSitePlus |
| Dephosphorylation site |
| LAMC3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000354360 | T1292N | COSMIC | Ovarian Cancer | 21720365 | ENSP00000354360 | S888F | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000354360 | G814R | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000354360 | R833C | COSMIC | Pancreatic Cancer | ENSP00000354360 | T1292N | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000354360 | G814R | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| LAMC3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LAMC3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LAMC3_HUMAN | CD44_HUMAN | other | KEGG |
| LAMC3_HUMAN | SV2C_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04510 | Focal adhesion |
| hsa05222 | Small cell lung cancer |
| hsa05145 | Toxoplasmosis |
| hsa05200 | Pathways in cancer |
| hsa05146 | Amoebiasis |
| hsa04512 | ECM-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005198 | structural molecule activity | TAS | molecular_function |
| GO:0014002 | astrocyte development | IEA | biological_process |
| GO:0060041 | retina development in camera-type eye | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0000904 | cell morphogenesis involved in differentiation | IEA | biological_process |
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0007601 | visual perception | IEA | biological_process |
| GO:0005578 | proteinaceous extracellular matrix | TAS | cellular_component |
| GO:0005604 | basement membrane | IEA | cellular_component |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |