Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KITH_HUMAN
Description:thymidine kinase 1, soluble [Source:HGNC Symbol;Acc:11830]
Location:chr17 q25.3
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S13TVLPGsPSKTRPhosphoSitePlus; RegPhos
Y181GGADKyHSVCRTKPhosphoSitePlus
S183ADKYHsVCRLCTKPhosphoSitePlus
S13TVLPGsPSKTRCDC2(CDK1RegPhos
S15LPGSPsKTRGQHPRD
Y48FQIAQyKCLVITKPhosphoSitePlus
Y55CLVIKyAKDTRTKPhosphoSitePlus
S13TVLPGsPSKTRCDC2RegPhos
S231QILQCsPHPRD; phosphoELM; SysPTM
S13TVLPGsPSKTRCDK2phosphoELM; RegPhos
S231QILQCsPANRegPhos; SysPTM
S231QILQCsPAN__PhosphoSitePlus; SysPTM
S13TVLPGsPSKTRCDK1HPRD; phosphoELM

Dephosphorylation site
KITH_HUMAN do not have dephosphorylation site.

Mutation site
KITH_HUMAN do not have mutation site.

Differential expressed protein
KITH_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KITH_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK2_HUMANKITH_HUMANkinase -> substrateRegPhos
CDK1_HUMANKITH_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANKITH_HUMANkinase -> substrateRegPhos
SP1_HUMANKITH_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa01100Metabolic pathways
hsa00983Drug metabolism - other enzymes
hsa00240Pyrimidine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060138fetal process involved in parturitionIEAbiological_process
GO:0006260DNA replicationIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0043097pyrimidine nucleoside salvageTASbiological_process
GO:0051414response to cortisol stimulusIEAbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0004797thymidine kinase activityIEAmolecular_function
GO:0006139nucleobase-containing compound metabolic processTASbiological_process
GO:0051289protein homotetramerizationIPIbiological_process
GO:0006206pyrimidine nucleobase metabolic processTASbiological_process
GO:0055086nucleobase-containing small molecule metabolic proTASbiological_process
GO:0048565digestive tract developmentIEAbiological_process
GO:0009636response to toxinIEAbiological_process
GO:0046688response to copper ionIEAbiological_process
GO:0019206nucleoside kinase activityEXPmolecular_function
GO:0001889liver developmentIEAbiological_process
GO:0014856skeletal muscle cell proliferationIEAbiological_process
GO:0008270zinc ion bindingIDAmolecular_function
GO:0031667response to nutrient levelsIEAbiological_process
GO:0009165nucleotide biosynthetic processEXPbiological_process
GO:0046104thymidine metabolic processIEAbiological_process


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