Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KI2L3_HUMAN
Description:killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 [Source:HGNC Symbol;Acc:6331]
Location:chrHSCHR19LRC_COX1_C
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S41GPLVKsEETVIPhosphoSitePlus
T44VKSEEtVILQCigPhosphoSitePlus
S51ILQCWsDVRFQigPhosphoSitePlus
Y98DLAGTyRCYGSigPhosphoSitePlus
S86SKANFsIGPMMigPhosphoSitePlus
T180PKVNGtFQADFPhosphoSitePlus

Dephosphorylation site
KI2L3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000342215P323SCOSMICOvarian Cancer21720365
ENSP00000342215R99KCOSMICSkin Cancer21984974
ENSP00000342215P323STCGAOvarian Cancer21720365, 18772890
ENSP00000342215G188STCGA, COSMICOvarian Cancer21720365, 18772890

Differential expressed protein
KI2L3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KI2L3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
1C18_HUMANKI2L3_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05332Graft-versus-host disease
hsa04612Antigen processing and presentation
hsa04650Natural killer cell mediated cytotoxicity

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004872receptor activityTASmolecular_function
GO:0016021integral to membraneTAScellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0050776regulation of immune responseTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0003823antigen bindingTASmolecular_function
GO:0006955immune responseTASbiological_process


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