| UniProt/SwissProt ID: | KDM5D_HUMAN |
| Description: | lysine (K)-specific demethylase 5D [Source:HGNC Symbol;Acc:11115] |
| Location: | chrY q11.222 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y239 | KKLQIyGPGPK | PhosphoSitePlus | |
| S420 | FWRLVsSIEED | PhosphoSitePlus | |
| Y741 | YLRYRyTLDEL | zf-C5HC2 | PhosphoSitePlus |
| T1244 | RPRLEtILALL | PLU-1 | PhosphoSitePlus |
| Dephosphorylation site |
| KDM5D_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000322408 | Y157N | COSMIC | Melanoma | |
| Differential expressed protein |
| KDM5D_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KDM5D_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ST17A_HUMAN | KDM5D_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | KDM5D_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KDM5D_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0016702 | oxidoreductase activity, acting on single donors w | IEA | molecular_function |
| GO:0055114 | oxidation-reduction process | IEA | biological_process |
| GO:0032453 | histone demethylase activity (H3-K4 specific) | IDA | molecular_function |
| GO:0007283 | spermatogenesis | NAS | biological_process |
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0016706 | oxidoreductase activity, acting on paired donors, | IEA | molecular_function |
| GO:0034720 | histone H3-K4 demethylation | IDA | biological_process |