Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KDM4C_HUMAN
Description:lysine (K)-specific demethylase 4C [Source:HGNC Symbol;Acc:17071]
Location:chr9 p24.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y908TSQTFyEVMFDPhosphoSitePlus
S392EEEEVsDEVDGPhosphoSitePlus
T903RVMAVtSQTFYPhosphoSitePlus
T353PTPAStPEVKAPhosphoSitePlus
S582RPPARsPMTLVPhosphoSitePlus
S248KMTLIsPSVLKJmjCPhosphoSitePlus
T906AVTSQtFYEVMPhosphoSitePlus
S250TLISPsVLKKYJmjCPhosphoSitePlus
T1009MRFEDtFYGADPhosphoSitePlus
T985REDIYtLDEELPhosphoSitePlus
S916MFDDGsFSRDTPhosphoSitePlus

Dephosphorylation site
KDM4C_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000370707E784DTCGAOvarian Cancer21720365, 18772890
ENSP00000370710E784DCOSMICOvarian Cancer21720365

Differential expressed protein
KDM4C_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KDM4C_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK4_HUMANKDM4C_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KDM4C_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0032454histone demethylase activity (H3-K9 specific)IMPmolecular_function
GO:0019899enzyme bindingIEAmolecular_function
GO:0008284positive regulation of cell proliferationIMPbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIDAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0050681androgen receptor bindingIEAmolecular_function
GO:0046417chorismate metabolic processIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0019899enzyme bindingIPImolecular_function
GO:0016702oxidoreductase activity, acting on single donors wIEAmolecular_function
GO:0033169histone H3-K9 demethylationIMPbiological_process
GO:0000790nuclear chromatinIDAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0050681androgen receptor bindingIPImolecular_function


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