Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KAT2B_HUMAN
Description:K(lysine) acetyltransferase 2B [Source:HGNC Symbol;Acc:8638]
Location:chr3 p24.3
Node attribute:acetylation(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T317LRSVFtVMRRQPCAF_NPhosphoSitePlus
Y729DPDQLySTLKSPhosphoSitePlus; HPRD; phosphoELM
Y533RMPKEyITRLVPhosphoSitePlus
S807YNPPEsEYYKCBromodomainPhosphoSitePlus
S49AAAGGsGACGPPhosphoSitePlus
Y301DSLPRyETTQVPCAF_NPhosphoSitePlus
S72PGGGGsARIAVPhosphoSitePlus
Y810PESEYyKCANIBromodomainPhosphoSitePlus
Y809PPESEyYKCANBromodomainPhosphoSitePlus
T731DQLYStLKSILPhosphoSitePlus
Y802TNCKEyNPPESBromodomainPhosphoSitePlus

Dephosphorylation site
KAT2B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263754V153MTCGAOvarian Cancer21720365, 18772890
ENSP00000263754D463NCOSMICCentral Nervous System Neoplasms18772396
ENSP00000263754V153MCOSMICOvarian Cancer21720365
ENSP00000263754K618RCOSMICSkin Cancer21984974
ENSP00000263754R137WCOSMICPancreatic Cancer21252315
ENSP00000263754D551NBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
KAT2B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KAT2B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KAT2B_HUMANANDR_HUMANacetylationNetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04330Notch signaling pathway
hsa05203Viral carcinogenesis
hsa05166HTLV-I infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006473protein acetylationTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0019901protein kinase bindingISSmolecular_function
GO:0042826histone deacetylase bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0019048virus-host interactionIEAbiological_process
GO:0003713transcription coactivator activityIDAmolecular_function
GO:0043966histone H3 acetylationIDAbiological_process
GO:0000123histone acetyltransferase complexIEAcellular_component
GO:0000776kinetochoreIEAcellular_component
GO:0004468lysine N-acetyltransferase activityISSmolecular_function
GO:0016407acetyltransferase activityIDAmolecular_function
GO:0032869cellular response to insulin stimulusIDAbiological_process
GO:0004402histone acetyltransferase activityIEAmolecular_function
GO:0045736negative regulation of cyclin-dependent protein kiIEAbiological_process
GO:0010467gene expressionTASbiological_process
GO:0004468lysine N-acetyltransferase activityIEAmolecular_function
GO:0008134transcription factor bindingIPImolecular_function
GO:0005634nucleusIEAcellular_component
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0007050cell cycle arrestTASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0008080N-acetyltransferase activityIEAmolecular_function
GO:0042641actomyosinIEAcellular_component
GO:0031674I bandIEAcellular_component
GO:0004861cyclin-dependent protein kinase inhibitor activityIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016573histone acetylationIEAbiological_process
GO:0018393internal peptidyl-lysine acetylationIEAbiological_process
GO:0016585chromatin remodeling complexIDAcellular_component
GO:0004861cyclin-dependent protein kinase inhibitor activityISSmolecular_function
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0005634nucleusISScellular_component
GO:0005671Ada2/Gcn5/Ada3 transcription activator complexIDAcellular_component
GO:0031672A bandIEAcellular_component
GO:0006361transcription initiation from RNA polymerase I proTASbiological_process
GO:0000125PCAF complexNAScellular_component
GO:0006338chromatin remodelingNASbiological_process
GO:0010835regulation of protein ADP-ribosylationIDAbiological_process
GO:0008285negative regulation of cell proliferationIDAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0018394peptidyl-lysine acetylationIDAbiological_process
GO:0018076N-terminal peptidyl-lysine acetylationIDAbiological_process
GO:0006360transcription from RNA polymerase I promoterTASbiological_process
GO:0019901protein kinase bindingIEAmolecular_function
GO:0003712transcription cofactor activityIPImolecular_function