| UniProt/SwissProt ID: | ITA11_HUMAN |
| Description: | integrin, alpha 11 [Source:HGNC Symbol;Acc:6136] |
| Location: | chr15 q23 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S1100 | ALKYKsMKIMV | PhosphoSitePlus | |
| T769 | DDGWPtTLRVS | Integrin_alpha2 | PhosphoSitePlus |
| Y1098 | LKALKyKSMKI | PhosphoSitePlus | |
| T686 | APHFQtTTVGI | Integrin_alpha2 | PhosphoSitePlus |
| S434 | VTSVVsSRQGR | PhosphoSitePlus | |
| T430 | LGYTVtSVVSS | PhosphoSitePlus | |
| T770 | DGWPTtLRVSV | Integrin_alpha2 | PhosphoSitePlus |
| S431 | GYTVTsVVSSR | PhosphoSitePlus | |
| Dephosphorylation site |
| ITA11_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000327290 | L1058P | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| ITA11_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ITA11_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ITA11_HUMAN | SRC_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05410 | Hypertrophic cardiomyopathy (HCM) |
| hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (A |
| hsa04510 | Focal adhesion |
| hsa05414 | Dilated cardiomyopathy |
| hsa04512 | ECM-receptor interaction |
| hsa04810 | Regulation of actin cytoskeleton |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005518 | collagen binding | TAS | molecular_function |
| GO:0008305 | integrin complex | IEA | cellular_component |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007160 | cell-matrix adhesion | TAS | biological_process |
| GO:0007517 | muscle organ development | TAS | biological_process |
| GO:0007155 | cell adhesion | TAS | biological_process |
| GO:0007229 | integrin-mediated signaling pathway | IEA | biological_process |