Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IPKA_HUMAN
Description:protein kinase (cAMP-dependent, catalytic) inhibitor alpha [Source:HGNC Symbol;Acc:9017]
Location:chr8 q21.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S59EDAQRsSTEQSPKIPhosphoSitePlus
Y8DVETTyADFIAEGFRHPRD; phosphoELM; RegPhos

Dephosphorylation site
IPKA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000336552G69RCOSMICCentral Nervous System Neoplasms18772396

Differential expressed protein
IPKA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IPKA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EGFR_HUMANIPKA_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05034Alcoholism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004862cAMP-dependent protein kinase inhibitor activityIEAmolecular_function
GO:0042308negative regulation of protein import into nucleusIEAbiological_process
GO:0043086negative regulation of catalytic activityIEAbiological_process
GO:0004862cAMP-dependent protein kinase inhibitor activityTASmolecular_function
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005634nucleusIEAcellular_component
GO:0010389regulation of G2/M transition of mitotic cell cyclIEAbiological_process
GO:0006469negative regulation of protein kinase activityIEAbiological_process


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