Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:INHBB_HUMAN
Description:inhibin, beta B [Source:HGNC Symbol;Acc:6067]
Location:chr2 q14.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S145VSEIIsFAETDTGFb_propeptidePhosphoSitePlus
S145VSEIIsFAETDHPRD
T149ISFAEtDGLASHPRD
T149ISFAEtDGLASTGFb_propeptidePhosphoSitePlus
S84KRHILsRLQMRTGFb_propeptidePhosphoSitePlus
Y202VRVKVyFQEQGTGFb_propeptidePhosphoSitePlus

Dephosphorylation site
INHBB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000295228Q236*COSMICMelanoma21499247
ENSP00000295228F275ICOSMICPancreatic Cancer

Differential expressed protein
INHBB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
INHBB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
INHBB_HUMANAVR2A_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006952defense responseTASbiological_process
GO:0046882negative regulation of follicle-stimulating hormonIPIbiological_process
GO:0048599oocyte developmentIEAbiological_process
GO:0046676negative regulation of insulin secretionIEAbiological_process
GO:0032869cellular response to insulin stimulusISSbiological_process
GO:0045444fat cell differentiationISSbiological_process
GO:0045444fat cell differentiationIEAbiological_process
GO:0042981regulation of apoptotic processIEAbiological_process
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0032924activin receptor signaling pathwayIDAbiological_process
GO:0040007growthIEAbiological_process
GO:0060279positive regulation of ovulationISSbiological_process
GO:0009605response to external stimulusIDAbiological_process
GO:0009267cellular response to starvationISSbiological_process
GO:0001541ovarian follicle developmentNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0048471perinuclear region of cytoplasmIDAcellular_component
GO:0005125cytokine activityTASmolecular_function
GO:0044320cellular response to leptin stimulusIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0005179hormone activityTASmolecular_function
GO:0046789host cell surface receptor bindingTASmolecular_function
GO:0046676negative regulation of insulin secretionISSbiological_process
GO:0060279positive regulation of ovulationIEAbiological_process
GO:0046881positive regulation of follicle-stimulating hormonIPIbiological_process
GO:0009267cellular response to starvationIEAbiological_process
GO:0042803protein homodimerization activityIPImolecular_function
GO:0048178negative regulation of hepatocyte growth factor biIDAbiological_process
GO:0030154cell differentiationNASbiological_process


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