| UniProt/SwissProt ID: | IL22_HUMAN |
| Description: | interleukin 22 [Source:HGNC Symbol;Acc:14900] |
| Location: | chr12 q15 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| IL22_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| IL22_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000329384 | E160D | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| IL22_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IL22_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IL22_HUMAN | I22R2_HUMAN | ligand -> receptor | HPMR |
| IL22_HUMAN | I22R2_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04630 | Jak-STAT signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0045518 | interleukin-22 receptor binding | NAS | molecular_function |
| GO:0006953 | acute-phase response | NAS | biological_process |
| GO:0007267 | cell-cell signaling | IC | biological_process |
| GO:0006954 | inflammatory response | NAS | biological_process |
| GO:0005576 | extracellular region | IC | cellular_component |
| GO:0005125 | cytokine activity | IEA | molecular_function |