Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:I15RA_HUMAN
Description:interleukin 15 receptor, alpha [Source:HGNC Symbol;Acc:5978]
Location:chr10 p15.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y227SLLACyLKSRQSYKHPRD
Y191SLLACyLKSRQSYKHPRD

Dephosphorylation site
I15RA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000380423*203LCOSMICHepatocellular Carcinoma21822264
ENSP00000369312R256GCOSMICHead and Neck Cancer21798893

Differential expressed protein
I15RA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
I15RA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KSYK_HUMANI15RA_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04630Jak-STAT signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04672Intestinal immune network for IgA production
hsa05166HTLV-I infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0005615extracellular spaceIEAcellular_component
GO:0000139Golgi membraneIEAcellular_component
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0030659cytoplasmic vesicle membraneIEAcellular_component
GO:0004896cytokine receptor activityTASmolecular_function
GO:0032825positive regulation of natural killer cell differeIEAbiological_process
GO:0004871signal transducer activityTASmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0008283cell proliferationTASbiological_process
GO:0007165signal transductionTASbiological_process
GO:0031965nuclear membraneIEAcellular_component


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