| UniProt/SwissProt ID: | HXB6_HUMAN |
| Description: | homeobox B6 [Source:HGNC Symbol;Acc:5117] |
| Location: | chr17 q21.32 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S214 | SASQLsAEEEE | PhosphoSitePlus; phosphoELM | |
| S211 | KLLSAsQLSAE | PhosphoSitePlus; HPRD; phosphoELM | |
| S214 | SASQLsAEEEE | CSNK2B | HPRD |
| Dephosphorylation site |
| HXB6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000420009 | K163E | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000225648 | K163E | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| HXB6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| HXB6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CSK2B_HUMAN | HXB6_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| HXB6_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0034101 | erythrocyte homeostasis | IEA | biological_process |
| GO:0008595 | anterior/posterior axis specification, embryo | NAS | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | NAS | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | NAS | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0009952 | anterior/posterior pattern specification | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0048706 | embryonic skeletal system development | IEA | biological_process |
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0048704 | embryonic skeletal system morphogenesis | IEA | biological_process |