| UniProt/SwissProt ID: | HMMR_HUMAN |
| Description: | hyaluronan-mediated motility receptor (RHAMM) [Source:HGNC Symbol;Acc:5012] |
| Location: | chr5 q34 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T110 | IQDLEtELEKM | HPRD | |
| S205 | RSLEEsQGKIA | PhosphoSitePlus | |
| S354 | EKELSsSLHQK | HPRD | |
| T703 | NFALKtPLKEG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S353 | QEKELsSSLHQ | PhosphoSitePlus; HPRD | |
| S65 | TTLPAsARKVK | PhosphoSitePlus; HPRD | |
| S20 | SGCAPsPGAYD | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| T95 | IQDLEtELEKM | HPRD | |
| T688 | NFALKtPLKEG | HPRD | |
| T198 | MKLQVtQRSLE | PhosphoSitePlus | |
| Y713 | GNTNCyRAPME | PhosphoSitePlus | |
| S339 | EKELSsSLHQK | HPRD | |
| Y250 | DQVEKyKLDIA | PhosphoSitePlus | |
| S338 | QEKELsSSLHQ | HPRD | |
| Dephosphorylation site |
| HMMR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000377492 | S520* | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000351554 | S519* | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000402673 | S433* | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000351554 | Q364* | COSMIC | Skin Cancer | 21984974 | ENSP00000185942 | S504* | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| HMMR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| HMMR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HAS2_HUMAN | HMMR_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04512 | ECM-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030214 | hyaluronan catabolic process | TAS | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0030212 | hyaluronan metabolic process | TAS | biological_process |
| GO:0009986 | cell surface | IEA | cellular_component |
| GO:0030203 | glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005975 | carbohydrate metabolic process | TAS | biological_process |
| GO:0005540 | hyaluronic acid binding | IEA | molecular_function |