Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HMGN2_HUMAN
Description:high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:4986]
Location:chr1 p36.11
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S29RSARLsAKPAPPKCaRegPhos
S25EPQRRsARLSAPKCaRegPhos
S29RSARLsAKPAPRSK2RegPhos
S29RSARLsAKPAPPKG_groupRegPhos
S25EPQRRsARLSARPS6KA3HPRD
S25EPQRRsARLSAPRKACAHPRD
S29RSARLsAKPAPPKACaRegPhos
S29RSARLsAKPAPHMG14_17PhosphoSitePlus
S25EPQRRsARLSAHMG14_17PhosphoSitePlus
S25EPQRRsARLSAPRKCAHPRD
S29RSARLsAKPAPPRKACAHPRD
S29RSARLsAKPAPRPS6KA3HPRD
S29RSARLsAKPAPPRKCAHPRD
S25EPQRRsARLSARSK2RegPhos
S29RSARLsAKPAPPKG/cGK_groupphosphoELM
S25EPQRRsARLSAPKACaRegPhos

Dephosphorylation site
HMGN2_HUMAN do not have dephosphorylation site.

Mutation site
HMGN2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000355228Breast CancerNormal vs. CancertissueUp20560667
ENSP00000355228Renal CancerNormal vs. CancertissueDown0.3919610612

Hyperphosphorylation site
HMGN2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6A3_HUMANHMGN2_HUMANkinase -> substrateRegPhos
KPCA_HUMANHMGN2_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
HMGN2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000785chromatinIEAcellular_component
GO:0005634nucleusNAScellular_component
GO:0003677DNA bindingNASmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0031492nucleosomal DNA bindingIEAmolecular_function
GO:0006325chromatin organizationNASbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process


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