Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HMGN1_HUMAN
Description:high mobility group nucleosome binding domain 1 [Source:HGNC Symbol;Acc:4984]
Location:chr21 q22.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S25RSARLsAKPPAMSK1RegPhos
S7AEGARPS6KA5HPRD
S7AEGARPS6KA4HPRD
S99EKEAKsDRegPhos
S21EPKRRsARLSAPKCaRegPhos
S7PKRKVsSAEGAMSK1RegPhos
S7PKRKVsSAEGAMSK2RegPhos
S21EPKRRsARLSAPKACaRegPhos
S7AEGAPRKACAHPRD
S7PKRKVsSAEGARegPhos
S21EPKRRsARLSAPKC_groupphosphoELM; RegPhos
S7AEGARPS6KA3HPRD
S99EKEAKHPRD; phosphoELM
S25RSARLsAKPPAPKACaRegPhos
S7PKRKVsSAEGARSK2RegPhos
S86TKTEEsPASDEHMG14_17PhosphoSitePlus
S89EESPAsDEAGEHPRD; RegPhos
S21EPKRRsARLSAHMG14_17PhosphoSitePlus
S21EPKRRsARLSAMSK1RegPhos
S8KRKVSsAEGAAHPRD; phosphoELM; RegPhos
S25RSARLsAKPPAPRKCAHPRD
S89EESPAsDEAGEHMG14_17PhosphoSitePlus
S21EPKRRsARLSAPRKACAHPRD
T70VANQEtKEDLPHMG14_17PhosphoSitePlus
S7AEGAPRKCAHPRD
S7PKRKVsSAEGAPKACaRegPhos
S25RSARLsAKPPAPKCaRegPhos
T81AENGEtKTEESHPRD; RegPhos
S8KRKVSsAEGAAMSK1RegPhos
S86TKTEEsPASDEHPRD; phosphoELM; RegPhos
S21EPKRRsARLSAPKA_groupphosphoELM; RegPhos
S25RSARLsAKPPARSK2RegPhos
S25RSARLsAKPPAPKA_groupphosphoELM; RegPhos
S25RSARLsAKPPAPRKACAHPRD
S7AEGAphosphoELM
S25RSARLsAKPPARPS6KA3HPRD
S7PKRKVsSAEGAHMG14_17PhosphoSitePlus
S99EKEAKsD____PhosphoSitePlus
S21EPKRRsARLSAPRKCAHPRD
S21EPKRRsARLSARSK2RegPhos
T83NGETKtEESPAHPRD
S8KRKVSsAEGAAHMG14_17PhosphoSitePlus
S21EPKRRsARLSARPS6KA3HPRD
T70VANQEtKEDLPHPRD; phosphoELM; RegPhos
S7PKRKVsSAEGAPKCaRegPhos
S25RSARLsAKPPAPKC_groupphosphoELM; RegPhos
S25RSARLsAKPPAHMG14_17PhosphoSitePlus

Dephosphorylation site
HMGN1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000370125K82RBIOMARTBreast Cancer21930507, 21930502
ENSP00000370125E15*COSMICBreast Cancer20668451

Differential expressed protein
HMGN1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HMGN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PAK4_HUMANHMGN1_HUMANkinase -> substrateRobert H Newman (2013)
KS6A5_HUMANHMGN1_HUMANkinase -> substrateRegPhos
ST17A_HUMANHMGN1_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANHMGN1_HUMANkinase -> substrateHPRD
KS6A4_HUMANHMGN1_HUMANkinase -> substrateHPRD; RegPhos
KS6A3_HUMANHMGN1_HUMANkinase -> substrateRegPhos
ZAGL2_HUMANHMGN1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05168Herpes simplex infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0040034regulation of development, heterochronicIEAbiological_process
GO:0031492nucleosomal DNA bindingIEAmolecular_function
GO:0003682chromatin bindingIEAmolecular_function
GO:0006283transcription-coupled nucleotide-excision repairIEAbiological_process
GO:0048597post-embryonic camera-type eye morphogenesisIEAbiological_process
GO:0006325chromatin organizationIEAbiological_process
GO:0010224response to UV-BIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0000785chromatinIEAcellular_component
GO:0010225response to UV-CIEAbiological_process
GO:0000720pyrimidine dimer repair by nucleotide-excision repIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0005634nucleusIEAcellular_component
GO:0032786positive regulation of DNA-dependent transcriptionTASbiological_process
GO:0050678regulation of epithelial cell proliferationIEAbiological_process


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