Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HLTF_HUMAN
Description:helicase-like transcription factor [Source:HGNC Symbol;Acc:11099]
Location:chr3 q24
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y195RAGPSySMPVHPhosphoSitePlus
T641LIKNItLRRTKSNF2_NPhosphoSitePlus
T736PSGNDtPEELRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y394KTAVQyIESSDPhosphoSitePlus; HPRD; phosphoELM
S378SKFRMsELSSSHPRD
T645ITLRRtKTSKISNF2_NPhosphoSitePlus
Y121AGALAyIMDNKHIRANPhosphoSitePlus
T390PKRRKtAVQYIHPRD; phosphoELM
S397VQYIEsSDSEEPhosphoSitePlus; HPRD; phosphoELM
S398QYIESsDSEEIPhosphoSitePlus; HPRD; phosphoELM
S373DIKEKsKFRMSHPRD
S400IESSDsEEIETPhosphoSitePlus; HPRD; phosphoELM
S421LKNVQsETKGRPhosphoSitePlus
T469EGSKKtDVEERPhosphoSitePlus; HPRD
T645ITLRRtKTSKIHPRD
T405SEEIEtSELPQPhosphoSitePlus
T641LIKNItLRRTKHPRD
T50PDDFLtSDEEVHPRD
T238AEAIEtPLLPHPhosphoSitePlus
Y93DPNNPyDKNAIHIRANPhosphoSitePlus
S858KSLVVsQFTTFPhosphoSitePlus

Dephosphorylation site
HLTF_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000376644T469ICOSMICSkin Cancer21984974
ENSP00000420429L309FCOSMICSkin Cancer21984974
ENSP00000308944E422VBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000376644E422VBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000308944L309FCOSMICSkin Cancer21984974
ENSP00000420429N24SCOSMICOvarian Cancer20668451
ENSP00000420429T469ICOSMICSkin Cancer21984974
ENSP00000376644N24SCOSMICOvarian Cancer20668451
ENSP00000308944T469ICOSMICSkin Cancer21984974
ENSP00000308944N24SCOSMICOvarian Cancer20668451
ENSP00000420429E422VBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000376644L309FCOSMICSkin Cancer21984974
ENSP00000420745E422VBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
HLTF_HUMAN is not differential expressed protein.

Hyperphosphorylation site
HLTF_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HLTF_HUMANPAI1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
HLTF_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIEAmolecular_function
GO:0016874ligase activityIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0016887ATPase activityIEAmolecular_function
GO:0016567protein ubiquitinationIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016818hydrolase activity, acting on acid anhydrides, in IEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0004386helicase activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0006200ATP catabolic processIEAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0016568chromatin modificationIEAbiological_process


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