| UniProt/SwissProt ID: | H31T_HUMAN |
| Description: | histone cluster 3, H3 [Source:HGNC Symbol;Acc:4778] |
| Location: | chr1 q42.13 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T4 | MARTKqTAR | RegPhos | |
| Y42 | KKPHRyRPGTV | PhosphoSitePlus | |
| S11 | QTARKsTGGKA | RSK2 | RegPhos |
| S88 | LRFQSsAVMAL | Histone | PhosphoSitePlus |
| S11 | QTARKsTGGKA | PhosphoSitePlus; RegPhos | |
| S11 | QTARKsTGGKA | MSK1 | RegPhos |
| S58 | RRYQKsTELLI | Histone | PhosphoSitePlus |
| S87 | DLRFQsSAVMA | Histone | PhosphoSitePlus |
| S29 | KVARKsAPATG | PhosphoSitePlus; RegPhos; SysPTM | |
| S11 | QTARKsTGGKA | RPS6KA5 | HPRD |
| S11 | QTARKsTGGKA | RPS6KA3 | HPRD |
| T46 | RYRPGtVALRE | PhosphoSitePlus | |
| S29 | KVARKsAPATG | MSK1 | RegPhos; SysPTM |
| T12 | TARKStGGKAP | RegPhos | |
| T81 | AQDFKtDLRFQ | Histone | PhosphoSitePlus |
| S29 | KVARKsAPATG | RPS6KA5 | HPRD; SysPTM |
| T119 | HAKRVtIMPKD | Histone | PhosphoSitePlus |
| Dephosphorylation site |
| H31T_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000355657 | E74K | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| H31T_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| H31T_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KS6A5_HUMAN | H31T_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | H31T_HUMAN | kinase -> substrate | RegPhos |
| KS6A3_HUMAN | H31T_HUMAN | kinase -> substrate | HPRD; RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05202 | Transcriptional misregulation in cancer |
| hsa05322 | Systemic lupus erythematosus |
| hsa05034 | Alcoholism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006334 | nucleosome assembly | NAS | biological_process |
| GO:0000786 | nucleosome | NAS | cellular_component |
| GO:0003677 | DNA binding | NAS | molecular_function |
| GO:0000723 | telomere maintenance | TAS | biological_process |
| GO:0046982 | protein heterodimerization activity | IEA | molecular_function |