Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:H2B1O_HUMAN
Description:histone cluster 1, H2bo [Source:HGNC Symbol;Acc:4758]
Location:chr6 p22.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S65MGIMNsFVNDIHistonePhosphoSitePlus
T91KRSTItSREIQHistonePhosphoSitePlus
Y122KAVTKyTSSK_PhosphoSitePlus
Y38SRKESySIYVYHistonePhosphoSitePlus
T116AVSEGtKAVTKPhosphoSitePlus
T89YNKRStITSREHistonePhosphoSitePlus
Y84SRLAHyNKRSTHistonePhosphoSitePlus
Y41ESYSIyVYKVLHistonePhosphoSitePlus
S88HYNKRsTITSRHistonePhosphoSitePlus
T120GTKAVtKYTSSPhosphoSitePlus
S57DTGISsKAMGIHistonePhosphoSitePlus
S56PDTGIsSKAMGHistonePhosphoSitePlus
S113AKHAVsEGTKAPhosphoSitePlus
T53QVHPDtGISSKHistonePhosphoSitePlus
S39RKESYsIYVYKHistonePhosphoSitePlus
S15APKKGsKKAVTMST1(STK4RegPhos
Y43YSIYVyKVLKQHistonePhosphoSitePlus
S37RSRKEsYSIYVHistonePhosphoSitePlus
S124VTKYTsSK___PhosphoSitePlus

Dephosphorylation site
H2B1O_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000303408E36KCOSMICOvarian Cancer21720365
ENSP00000303408E36KTCGAOvarian Cancer21720365, 18772890
ENSP00000303408E77KCOSMICSkin Cancer21984974

Differential expressed protein
H2B1O_HUMAN is not differential expressed protein.

Hyperphosphorylation site
H2B1O_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK4_HUMANH2B1O_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05034Alcoholism
hsa05203Viral carcinogenesis
hsa05322Systemic lupus erythematosus

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0000786nucleosomeNAScellular_component
GO:0003677DNA bindingNASmolecular_function
GO:0006334nucleosome assemblyNASbiological_process
GO:0005634nucleusIEAcellular_component


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