Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:H2B1B_HUMAN
Description:histone cluster 1, H2bb [Source:HGNC Symbol;Acc:4751]
Location:chr6 p22.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T53QVHPDtGISSKHistonePhosphoSitePlus
Y41ESYSIyVYKVLHistonePhosphoSitePlus
S124VTKYTsSK___PhosphoSitePlus
T120GTKAVtKYTSSPhosphoSitePlus
S15APKKGsKKAITMST1phosphoELM; RegPhos
S15APKKGsKKAITPhosphoSitePlus
S65MGIMNsFVNDIHistonePhosphoSitePlus
S57DTGISsKAMGIHistonePhosphoSitePlus
S113AKHAVsEGTKAPhosphoSitePlus
S56PDTGIsSKAMGHistonePhosphoSitePlus
Y84SRLAHyNKRSTHistonePhosphoSitePlus
S33KKRKRsRKESYHistonePhosphoSitePlus
Y43YSIYVyKVLKQHistonePhosphoSitePlus
S88HYNKRsTITSRHistonePhosphoSitePlus
S37RSRKEsYSIYVHistonePhosphoSitePlus
Y38SRKESySIYVYHistonePhosphoSitePlus
T91KRSTItSREIQHistonePhosphoSitePlus
Y122KAVTKyTSSK_PhosphoSitePlus
T116AVSEGtKAVTKPhosphoSitePlus
S39RKESYsIYVYKHistonePhosphoSitePlus
S15APKKGsKKAITMST1(STK4RegPhos
T89YNKRStITSREHistonePhosphoSitePlus

Dephosphorylation site
H2B1B_HUMAN do not have dephosphorylation site.

Mutation site
H2B1B_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000350580Breast CancerNormal vs. CancertissueDown0.4220739354

Hyperphosphorylation site
H2B1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK4_HUMANH2B1B_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05203Viral carcinogenesis
hsa05322Systemic lupus erythematosus
hsa05034Alcoholism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0000786nucleosomeNAScellular_component
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0006334nucleosome assemblyNASbiological_process
GO:0003677DNA bindingNASmolecular_function


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