| UniProt/SwissProt ID: | GUC2A_HUMAN |
| Description: | guanylate cyclase activator 2A (guanylin) [Source:HGNC Symbol;Acc:4682] |
| Location: | chr1 p34.2 |
| Node attribute: | ligand |
| Phosphorylation site |
| GUC2A_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| GUC2A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000349493 | E34V | COSMIC | Pancreatic Cancer | |
| Differential expressed protein |
| GUC2A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GUC2A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GUC2A_HUMAN | GUC2C_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| GUC2A_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030250 | guanylate cyclase activator activity | IEA | molecular_function |
| GO:0007165 | signal transduction | NAS | biological_process |
| GO:0030250 | guanylate cyclase activator activity | NAS | molecular_function |
| GO:0005179 | hormone activity | NAS | molecular_function |
| GO:0031284 | positive regulation of guanylate cyclase activity | IEA | biological_process |
| GO:0008047 | enzyme activator activity | IEA | molecular_function |
| GO:0005576 | extracellular region | NAS | cellular_component |