Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GRHL1_HUMAN
Description:grainyhead-like 1 (Drosophila) [Source:HGNC Symbol;Acc:17923]
Location:chr2 p25.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S76PRERRsSTAKPPhosphoSitePlus
Y611EAGGSyKLTLTPhosphoSitePlus
Y564AISDKyDVPHDPhosphoSitePlus
S77RERRSsTAKPEPhosphoSitePlus
Y67GLLYDyYKVPRPhosphoSitePlus
T208NAQRRtPDSTFPhosphoSitePlus
Y594NIVKHySNEDTPhosphoSitePlus
Y65ALGLLyDYYKVPhosphoSitePlus
Y68LLYDYyKVPREPhosphoSitePlus
Y414PVHRAyCQIKVCP2PhosphoSitePlus

Dephosphorylation site
GRHL1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000324693V397IBIOMARTGastric Cancer21930507, 21930502
ENSP00000324494Q10RCOSMICPancreatic Cancer

Differential expressed protein
GRHL1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GRHL1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DYRK3_HUMANGRHL1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
GRHL1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005794Golgi apparatusIDAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0044255cellular lipid metabolic processTASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process


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