Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GPM6A_HUMAN
Description:glycoprotein M6A [Source:HGNC Symbol;Acc:4460]
Location:chr4 q34.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S256YEDIKsKEEQEPhosphoSitePlus; HPRD; SysPTM
T10MEEGQtQKGCFPKCaRegPhos
T10MEEGQtQKGCFPRKCAHPRD
S267LHDIHsTRSKEPhosphoSitePlus; RegPhos
T10MEEGQtQKGCFPKC_alphaphosphoELM
T10MEEGQtQKGCFPKCa(PKC alphaRegPhos

Dephosphorylation site
GPM6A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000377268R163WBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000280187S52FBIOMARTBreast Cancer21930507, 21930502
ENSP00000280187R163WBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000377268G53ECOSMICSkin Cancer21984974
ENSP00000377268S52FBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
GPM6A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GPM6A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANGPM6A_HUMANkinase -> substrateRegPhos
KPCA_HUMANGPM6A_HUMANkinase -> substrateHPRD; Robert H Newman (2013)

Function Annotation
KEGG Pathway
GPM6A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051491positive regulation of filopodium assemblyIEAbiological_process
GO:0070588calcium ion transmembrane transportIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0043025neuronal cell bodyIEAcellular_component
GO:0007416synapse assemblyIEAbiological_process
GO:0044295axonal growth coneIEAcellular_component
GO:0048812neuron projection morphogenesisIEAbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0030175filopodiumIEAcellular_component
GO:0043005neuron projectionIEAcellular_component
GO:0048863stem cell differentiationIDAbiological_process
GO:0003407neural retina developmentIEAbiological_process
GO:0043197dendritic spineIEAcellular_component
GO:0005262calcium channel activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0043005neuron projectionISScellular_component
GO:0001764neuron migrationIDAbiological_process


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