| UniProt/SwissProt ID: | GPBP1_HUMAN |
| Description: | GC-rich promoter binding protein 1 [Source:HGNC Symbol;Acc:29520] |
| Location: | chr5 q11.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S274 | CNRSNsSSPVD | PhosphoSitePlus | |
| S49 | RRRHNsSDGFD | PhosphoSitePlus | |
| S272 | KECNRsNSSSP | PhosphoSitePlus | |
| S50 | RRHNSsDGFDS | PhosphoSitePlus | |
| Y40 | WTENRyDVNRR | PhosphoSitePlus | |
| S262 | KNFSPsTNSVK | PhosphoSitePlus | |
| S196 | VGNLPsQPVKN | PhosphoSitePlus | |
| T291 | RLTKLtRMRTD | PhosphoSitePlus | |
| T295 | LTRMRtDKKSE | PhosphoSitePlus | |
| Y144 | SLNPEyEREPN | PhosphoSitePlus | |
| S139 | AEDFPsLNPEY | PhosphoSitePlus | |
| T263 | NFSPStNSVKE | PhosphoSitePlus | |
| T288 | QQPRLtKLTRM | PhosphoSitePlus | |
| S260 | TAKNFsPSTNS | PhosphoSitePlus | |
| Dephosphorylation site |
| GPBP1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000421202 | *474G | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| GPBP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GPBP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HIPK4_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST17A_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| EPHA3_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| TGFR2_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MAPK5_HUMAN | GPBP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| GPBP1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |