Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GPBP1_HUMAN
Description:GC-rich promoter binding protein 1 [Source:HGNC Symbol;Acc:29520]
Location:chr5 q11.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S274CNRSNsSSPVDPhosphoSitePlus
S49RRRHNsSDGFDPhosphoSitePlus
S272KECNRsNSSSPPhosphoSitePlus
S50RRHNSsDGFDSPhosphoSitePlus
Y40WTENRyDVNRRPhosphoSitePlus
S262KNFSPsTNSVKPhosphoSitePlus
S196VGNLPsQPVKNPhosphoSitePlus
T291RLTKLtRMRTDPhosphoSitePlus
T295LTRMRtDKKSEPhosphoSitePlus
Y144SLNPEyEREPNPhosphoSitePlus
S139AEDFPsLNPEYPhosphoSitePlus
T263NFSPStNSVKEPhosphoSitePlus
T288QQPRLtKLTRMPhosphoSitePlus
S260TAKNFsPSTNSPhosphoSitePlus

Dephosphorylation site
GPBP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000421202*474GCOSMICOvarian Cancer21720365

Differential expressed protein
GPBP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GPBP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HIPK4_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)
EPHA3_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANGPBP1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
GPBP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process


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