Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNMT_HUMAN
Description:glycine N-methyltransferase [Source:HGNC Symbol;Acc:4415]
Location:chr6 p21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T220KAHMVtLDYTVPhosphoSitePlus
S252PHCLAsFTELLPhosphoSitePlus
T224VTLDYtVQVPGPhosphoSitePlus
S10VYRTRsLGVAAPRKACAHPRD
Y196PGKNIyYKSDLPhosphoSitePlus
Y22GLPDQyADGEAPhosphoSitePlus
Y34RVWQLyIGDTRPhosphoSitePlus
S199NIYYKsDLTKDPhosphoSitePlus
Y197GKNIYyKSDLTPhosphoSitePlus

Dephosphorylation site
GNMT_HUMAN do not have dephosphorylation site.

Mutation site
GNMT_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000361894hepatitis C virusNormal vs. CancertissueDown0.218715028
ENSP00000361894Hepatocellular CarcinomaNormal vs. CancertissueDown0.4817627933
ENSP00000361894hepatitis B virusNormal vs. CancertissueDown0.2215852300
ENSP00000361894Hepatocellular CarcinomaNormal vs. CancertissueDown18571811
ENSP00000361894Hepatocellular CarcinomaNormal vs. CancertissueDown18937283

Hyperphosphorylation site
GNMT_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANGNMT_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa00260Glycine, serine and threonine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006111regulation of gluconeogenesisIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0046500S-adenosylmethionine metabolic processIEAbiological_process
GO:0006555methionine metabolic processIEAbiological_process
GO:0051289protein homotetramerizationIEAbiological_process
GO:0017174glycine N-methyltransferase activityIEAmolecular_function
GO:0046500S-adenosylmethionine metabolic processIDAbiological_process
GO:0017174glycine N-methyltransferase activityIDAmolecular_function
GO:0006730one-carbon metabolic processIEAbiological_process
GO:0051289protein homotetramerizationIPIbiological_process
GO:0008168methyltransferase activityIEAmolecular_function
GO:0008152metabolic processIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016594glycine bindingIDAmolecular_function
GO:0006464cellular protein modification processNASbiological_process
GO:0005977glycogen metabolic processIEAbiological_process
GO:0016594glycine bindingIEAmolecular_function
GO:0005542folic acid bindingIEAmolecular_function


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