| UniProt/SwissProt ID: | GMFB_HUMAN |
| Description: | glia maturation factor, beta [Source:HGNC Symbol;Acc:4373] |
| Location: | chr14 q22.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T27 | RFRKEtNNAAI | RSK3 | RegPhos |
| S72 | RFIVYsYKYQH | PKC_alpha | phosphoELM |
| T27 | RFRKEtNNAAI | PRKACA | HPRD |
| S53 | ELEGIsPDELK | CK2_alpha | phosphoELM |
| S83 | DDGRVsYPLCF | PKA_group | phosphoELM; RegPhos |
| S83 | DDGRVsYPLCF | PKACa | RegPhos |
| S53 | ELEGIsPDELK | CK2a1(CK2 alpha | RegPhos |
| T27 | RFRKEtNNAAI | PKACa | RegPhos |
| S53 | ELEGIsPDELK | CK2a1-rs | RegPhos |
| T27 | RFRKEtNNAAI | RSK_group | phosphoELM; RegPhos |
| T27 | RFRKEtNNAAI | Cofilin_ADF | PhosphoSitePlus |
| S53 | ELEGIsPDELK | CK2a1 | RegPhos |
| S72 | RFIVYsYKYQH | PRKCA | HPRD |
| S53 | ELEGIsPDELK | CSNK2A1 | HPRD |
| T27 | RFRKEtNNAAI | RPS6KA1 | HPRD |
| Y84 | DGRVSyPLCFI | phosphoELM; RegPhos | |
| Y84 | DGRVSyPLCFI | Cofilin_ADF | PhosphoSitePlus |
| T27 | RFRKEtNNAAI | PKA_group | phosphoELM; RegPhos |
| S53 | ELEGIsPDELK | Cofilin_ADF | PhosphoSitePlus |
| S72 | RFIVYsYKYQH | Cofilin_ADF | PhosphoSitePlus |
| S83 | DDGRVsYPLCF | Cofilin_ADF | PhosphoSitePlus |
| S72 | RFIVYsYKYQH | PKCa(PKC alpha | RegPhos |
| S72 | RFIVYsYKYQH | PKCa | RegPhos |
| S83 | DDGRVsYPLCF | PRKACA | HPRD |
| Dephosphorylation site |
| GMFB_HUMAN do not have dephosphorylation site. |
| Mutation site |
| GMFB_HUMAN do not have mutation site. |
| Differential expressed protein |
| GMFB_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GMFB_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | GMFB_HUMAN | kinase -> substrate | HPRD; Robert H Newman (2013) |
| KS6A1_HUMAN | GMFB_HUMAN | kinase -> substrate | HPRD |
| CSK21_HUMAN | GMFB_HUMAN | kinase -> substrate | HPRD; Robert H Newman (2013) |
| KS6A2_HUMAN | GMFB_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | GMFB_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| GMFB_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | TAS | biological_process |
| GO:0008047 | enzyme activator activity | TAS | molecular_function |
| GO:0004860 | protein kinase inhibitor activity | TAS | molecular_function |
| GO:0008083 | growth factor activity | IEA | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006469 | negative regulation of protein kinase activity | TAS | biological_process |
| GO:0007399 | nervous system development | TAS | biological_process |
| GO:0004871 | signal transducer activity | TAS | molecular_function |
| GO:0043085 | positive regulation of catalytic activity | TAS | biological_process |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |