Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GBLP_HUMAN
Description:guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [Source:HGNC Symbol;Acc:4399]
Location:chr5 q35.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y228EGKHLyTLDGGWD40PhosphoSitePlus
Y52RDETNyGIPQRDUF1416PhosphoSitePlus
Y246FSPNRyWLCAAWD40PhosphoSitePlus
T134IKLWNtLGVCKPhosphoSitePlus
T313RVWQVtIGTR_PhosphoSitePlus
T2QMTLHPRD
T316QVTIGHPRD
T2____MtEQMTLPhosphoSitePlus
Y194IGHTGyLNTVTTyk2phosphoELM; RegPhos
T316QVTIGtR____PhosphoSitePlus
Y194IGHTGyLNTVTWD40PhosphoSitePlus
Y302TLFAGyTDNLVWD40PhosphoSitePlus
T50LTRDEtNYGIPDUF1416PhosphoSitePlus
T24TQIATtPQFPDWD40PhosphoSitePlus
T46IMWKLtRDETNDUF1416PhosphoSitePlus
T6RGTLHPRD
Y228EGKHLyTLDGGHPRD; RegPhos
Y228EGKHLyTLDGGSrcRegPhos
T6MTEQMtLRGTLWD40PhosphoSitePlus
S146TVQDEsHSEWVWD40PhosphoSitePlus
Y228EGKHLyTLDGGSRCphosphoELM
Y246FSPNRyWLCAASrcRegPhos
Y246FSPNRyWLCAASRCphosphoELM
T313RVWQVtIGHPRD

Dephosphorylation site
GBLP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000426909S157LCOSMICSkin Cancer21984974
ENSP00000426909R125*COSMICSkin Cancer21984974

Differential expressed protein
GBLP_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GBLP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TYK2_HUMANGBLP_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANGBLP_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05162Measles

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0032464positive regulation of protein homooligomerizationIDAbiological_process
GO:0015935small ribosomal subunitIEAcellular_component
GO:0032880regulation of protein localizationISSbiological_process
GO:0051726regulation of cell cycleIDAbiological_process
GO:0017148negative regulation of translationIEAbiological_process
GO:0030971receptor tyrosine kinase bindingIDAmolecular_function
GO:2001244positive regulation of intrinsic apoptotic signaliIMPbiological_process
GO:0030496midbodyIDAcellular_component
GO:0032436positive regulation of proteasomal ubiquitin-depenIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0008200ion channel inhibitor activityIEAmolecular_function
GO:0051302regulation of cell divisionISSbiological_process
GO:0090003regulation of establishment of protein localizatioIEAbiological_process
GO:0019048virus-host interactionIEAbiological_process
GO:2000543positive regulation of gastrulationISSbiological_process
GO:0005102receptor bindingNASmolecular_function
GO:0048511rhythmic processIEAbiological_process
GO:2000114regulation of establishment of cell polarityISSbiological_process
GO:0005856cytoskeletonIEAcellular_component
GO:0048471perinuclear region of cytoplasmIDAcellular_component
GO:0030178negative regulation of Wnt receptor signaling pathISSbiological_process
GO:0042169SH2 domain bindingIDAmolecular_function
GO:0030335positive regulation of cell migrationIDAbiological_process
GO:0030308negative regulation of cell growthIDAbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0050765negative regulation of phagocytosisIMPbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0043204perikaryonIEAcellular_component
GO:0019903protein phosphatase bindingIPImolecular_function
GO:0005080protein kinase C bindingIDAmolecular_function
GO:0001891phagocytic cupIDAcellular_component
GO:0061099negative regulation of protein tyrosine kinase actIDAbiological_process
GO:0030425dendriteIEAcellular_component
GO:0051898negative regulation of protein kinase B signaling IMPbiological_process
GO:0001934positive regulation of protein phosphorylationIDAbiological_process
GO:0043065positive regulation of apoptotic processIMPbiological_process
GO:0008656cysteine-type endopeptidase activator activity invIMPmolecular_function
GO:0006919activation of cysteine-type endopeptidase activityIMPbiological_process
GO:0007369gastrulationIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0043547positive regulation of GTPase activityIDAbiological_process
GO:0030292protein tyrosine kinase inhibitor activityIDAmolecular_function


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