| UniProt/SwissProt ID: | GAST_HUMAN |
| Description: | gastrin [Source:HGNC Symbol;Acc:4164] |
| Location: | chrHG185_PATCH q21.2 |
| Node attribute: | ligand; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y87 | EEEEAyGWMDF | Src | RegPhos |
| S96 | DFGRRsAEDEN | RegPhos | |
| S96 | DFGRRsAED | HPRD; phosphoELM | |
| S96 | DFGRRsAEDEN | Gastrin | PhosphoSitePlus |
| Y87 | EEEEAyGWMDF | SRC | phosphoELM |
| Dephosphorylation site |
| GAST_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000331358 | A97T | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 |
| Differential expressed protein |
| GAST_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GAST_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GAST_HUMAN | GASR_HUMAN | ligand -> receptor | HPMR |
| ZAGL2_HUMAN | GAST_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04971 | Gastric acid secretion |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005179 | hormone activity | IEA | molecular_function |
| GO:0007165 | signal transduction | NAS | biological_process |