Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GASR_HUMAN
Description:cholecystokinin B receptor [Source:HGNC Symbol;Acc:1571]
Location:chr11 p15.4
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S434SIASLsRLSYTPhosphoSitePlus
T443YTTIStLGPG_PhosphoSitePlus
S442SYTTIsTLGPGPhosphoSitePlus
T439SRLSYtTISTLPhosphoSitePlus
T440RLSYTtISTLGPhosphoSitePlus
S437SLSRLsYTTISPhosphoSitePlus
Y294DSDGCyVQLPR7tm_1PhosphoSitePlus
Y438LSRLSyTTISTPhosphoSitePlus
Y61IRITLyAVIFLTMPhosphoSitePlus

Dephosphorylation site
GASR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000335544G267VCOSMICLung Cancer20668451
ENSP00000335544A327PCOSMICOvarian Cancer21720365
ENSP00000335544R395CCOSMICHead and Neck Cancer21798893
ENSP00000335544I241FCOSMICHead and Neck Cancer21798893
ENSP00000335544V69IBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000335544A431DCOSMICLung Cancer20668451
ENSP00000335544C405FCOSMICLung Cancer20668451
ENSP00000335544A327PTCGAOvarian Cancer21720365, 18772890
ENSP00000335544D256NBIOMARTBreast Cancer21930507, 21930502
ENSP00000335544V98FCOSMICOvarian Cancer21720365
ENSP00000435534D256NBIOMARTBreast Cancer21930507, 21930502
ENSP00000435534L375MBIOMARTBreast Cancer21930507, 21930502
ENSP00000335544R278HCOSMICLung Cancer20668451
ENSP00000335544L306MBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
GASR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GASR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CCKN_HUMANGASR_HUMANligand -> receptorHPMR
GAST_HUMANGASR_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04971Gastric acid secretion
hsa04020Calcium signaling pathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:00469351-phosphatidylinositol-3-kinase regulator activityTASmolecular_function
GO:0016020membraneIEAcellular_component
GO:0008283cell proliferationTASbiological_process
GO:0004951cholecystokinin receptor activityTASmolecular_function
GO:0005887integral to plasma membraneICcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007200phospholipase C-activating G-protein coupled recepTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0007204elevation of cytosolic calcium ion concentrationIDAbiological_process
GO:0031741type B gastrin/cholecystokinin receptor bindingIDAmolecular_function
GO:0007631feeding behaviorTASbiological_process
GO:0008284positive regulation of cell proliferationIDAbiological_process
GO:0007166cell surface receptor signaling pathwayNASbiological_process
GO:0015054gastrin receptor activityIDAmolecular_function
GO:0007586digestionTASbiological_process
GO:0007600sensory perceptionTASbiological_process
GO:0004435phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0005515protein bindingIEAmolecular_function


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