UniProt/SwissProt ID: | FLT3L_HUMAN |
Description: | fms-related tyrosine kinase 3 ligand [Source:HGNC Symbol;Acc:3766] |
Location: | chr19 q13.33 |
Node attribute: | ligand; PPI(source) |
Phosphorylation site |
FLT3L_HUMAN do not have phosphorylation site. |
Dephosphorylation site |
FLT3L_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000204637 | P168A | BIOMART | Gastric Cancer | 21930507, 21930502 |
ENSP00000204637 | S118fs*24 | COSMIC | Head and Neck Cancer | 21798893 |
Differential expressed protein |
FLT3L_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
FLT3L_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
FLT3L_HUMAN | FLT3_HUMAN | ligand -> receptor | HPMR |
FLT3L_HUMAN | FLT3_HUMAN | other | KEGG |
Function Annotation |
KEGG Pathway |
KEGG ID | Pathway |
---|---|
hsa04060 | Cytokine-cytokine receptor interaction |
hsa04640 | Hematopoietic cell lineage |
hsa05200 | Pathways in cancer |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | cellular_component |
GO:0035162 | embryonic hemopoiesis | IDA | biological_process |
GO:0016021 | integral to membrane | NAS | cellular_component |
GO:0005125 | cytokine activity | IEA | molecular_function |
GO:0008284 | positive regulation of cell proliferation | IDA | biological_process |
GO:0016020 | membrane | NAS | cellular_component |
GO:0007165 | signal transduction | TAS | biological_process |
GO:0005615 | extracellular space | IEA | cellular_component |
GO:0005102 | receptor binding | TAS | molecular_function |