| UniProt/SwissProt ID: | FGF22_HUMAN |
| Description: | fibroblast growth factor 22 [Source:HGNC Symbol;Acc:3679] |
| Location: | chr19 p13.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T64 | GRVQGtRWRHG | FGF | PhosphoSitePlus |
| Dephosphorylation site |
| FGF22_HUMAN do not have dephosphorylation site. |
| Mutation site |
| FGF22_HUMAN do not have mutation site. |
| Differential expressed protein |
| FGF22_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FGF22_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FGF22_HUMAN | FGFR2_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05218 | Melanoma |
| hsa04810 | Regulation of actin cytoskeleton |
| hsa05200 | Pathways in cancer |
| hsa04010 | MAPK signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0008543 | fibroblast growth factor receptor signaling pathwa | TAS | biological_process |
| GO:0008286 | insulin receptor signaling pathway | TAS | biological_process |
| GO:0030154 | cell differentiation | NAS | biological_process |
| GO:0009986 | cell surface | IEA | cellular_component |
| GO:0005615 | extracellular space | NAS | cellular_component |
| GO:0008083 | growth factor activity | IEA | molecular_function |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005730 | nucleolus | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |