Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FGF10_HUMAN
Description:fibroblast growth factor 10 [Source:HGNC Symbol;Acc:3666]
Location:chr5 p12
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y161IEENGyNTYASFGFPhosphoSitePlus
T114SILEItSVEIGFGFPhosphoSitePlus
Y164NGYNTyASFNWFGFPhosphoSitePlus

Dephosphorylation site
FGF10_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000264664H72YCOSMICLung Cancer20668451
ENSP00000264664S11LCOSMICLung Cancer20668451

Differential expressed protein
FGF10_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FGF10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FGF10_HUMANFGFR2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04010MAPK signaling pathway
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05200Pathways in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0010634positive regulation of epithelial cell migrationIEAbiological_process
GO:0048807female genitalia morphogenesisIEAbiological_process
GO:0001759organ inductionIEAbiological_process
GO:0003338metanephros morphogenesisIEAbiological_process
GO:0050918positive chemotaxisIEAbiological_process
GO:0007267cell-cell signalingIEAbiological_process
GO:0021983pituitary gland developmentIEAbiological_process
GO:0035265organ growthIEAbiological_process
GO:0031012extracellular matrixIDAcellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0008543fibroblast growth factor receptor signaling pathwaTASbiological_process
GO:0060173limb developmentIEAbiological_process
GO:0032781positive regulation of ATPase activityIDAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0048752semicircular canal morphogenesisIEAbiological_process
GO:0045596negative regulation of cell differentiationIEAbiological_process
GO:0061033secretion by lung epithelial cell involved in lungIDAbiological_process
GO:0035019somatic stem cell maintenanceIEAbiological_process
GO:0045747positive regulation of Notch signaling pathwayIEAbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0071157negative regulation of cell cycle arrestIDAbiological_process
GO:0060019radial glial cell differentiationIEAbiological_process
GO:0060441epithelial tube branching involved in lung morphogIEAbiological_process
GO:0000187activation of MAPK activityIDAbiological_process
GO:0060879semicircular canal fusionIEAbiological_process
GO:0034394protein localization to cell surfaceIDAbiological_process
GO:0048538thymus developmentIDAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0090263positive regulation of canonical Wnt receptor signIEAbiological_process
GO:0031532actin cytoskeleton reorganizationIDAbiological_process
GO:0008286insulin receptor signaling pathwayTASbiological_process
GO:0043616keratinocyte proliferationIEAbiological_process
GO:0070371ERK1 and ERK2 cascadeIDAbiological_process
GO:0060436bronchiole morphogenesisIEAbiological_process
GO:0060541respiratory system developmentIEAbiological_process
GO:0060428lung epithelium developmentIDAbiological_process
GO:0008544epidermis developmentIEAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0001823mesonephros developmentIEPbiological_process
GO:0060915mesenchymal cell differentiation involved in lung IEAbiological_process
GO:0031659positive regulation of cyclin-dependent protein kiIDAbiological_process
GO:0001656metanephros developmentIEPbiological_process
GO:0046579positive regulation of Ras protein signal transducIDAbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0045740positive regulation of DNA replicationIMPbiological_process
GO:0060174limb bud formationIEAbiological_process
GO:0060594mammary gland specificationIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0010838positive regulation of keratinocyte proliferationIDAbiological_process
GO:0050930induction of positive chemotaxisIEAbiological_process
GO:0048565digestive tract developmentIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0042475odontogenesis of dentin-containing toothIEAbiological_process
GO:0048557embryonic digestive tract morphogenesisIEAbiological_process
GO:0031069hair follicle morphogenesisIEAbiological_process
GO:0008589regulation of smoothened signaling pathwayIEAbiological_process
GO:0031016pancreas developmentIEAbiological_process
GO:0048645organ formationIEAbiological_process
GO:0050671positive regulation of lymphocyte proliferationIDAbiological_process
GO:0048566embryonic digestive tract developmentIEAbiological_process
GO:0060685regulation of prostatic bud formationIEAbiological_process
GO:0050677positive regulation of urothelial cell proliferatiIDAbiological_process
GO:0048754branching morphogenesis of a tubeIDAbiological_process
GO:0050918positive chemotaxisIDAbiological_process
GO:0032355response to estradiol stimulusIEAbiological_process
GO:0070352positive regulation of white fat cell proliferatioIEAbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIDAbiological_process
GO:0060661submandibular salivary gland formationIEAbiological_process
GO:0030878thyroid gland developmentIEAbiological_process
GO:0007431salivary gland developmentIMPbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0050674urothelial cell proliferationIDAbiological_process
GO:0060667branch elongation involved in salivary gland morphIEAbiological_process
GO:0032925regulation of activin receptor signaling pathwayIEAbiological_process
GO:0070075tear secretionIMPbiological_process
GO:0050678regulation of epithelial cell proliferationIEAbiological_process
GO:0060664epithelial cell proliferation involved in salivaryIEAbiological_process
GO:0070384Harderian gland developmentIEAbiological_process
GO:0045739positive regulation of DNA repairIDAbiological_process
GO:0030324lung developmentIEAbiological_process
GO:0060447bud outgrowth involved in lung branchingIDAbiological_process
GO:0060445branching involved in salivary gland morphogenesisIEAbiological_process
GO:0008285negative regulation of cell proliferationIEAbiological_process
GO:0042693muscle cell fate commitmentIEAbiological_process
GO:0042056chemoattractant activityIEAmolecular_function
GO:0030916otic vesicle formationIEAbiological_process
GO:0048286lung alveolus developmentIEAbiological_process
GO:0060496mesenchymal-epithelial cell signaling involved in IEAbiological_process
GO:0045931positive regulation of mitotic cell cycleIEAbiological_process
GO:0070374positive regulation of ERK1 and ERK2 cascadeIEAbiological_process
GO:0050673epithelial cell proliferationIEAbiological_process
GO:0005111type 2 fibroblast growth factor receptor bindingIPImolecular_function
GO:0042060wound healingIDAbiological_process
GO:0007435salivary gland morphogenesisIEAbiological_process
GO:0060510Type II pneumocyte differentiationIEAbiological_process
GO:0030177positive regulation of Wnt receptor signaling pathIEAbiological_process
GO:0031076embryonic camera-type eye developmentIEAbiological_process
GO:0051549positive regulation of keratinocyte migrationIDAbiological_process
GO:0048730epidermis morphogenesisIEAbiological_process
GO:0009887organ morphogenesisIEAbiological_process
GO:0009880embryonic pattern specificationIEAbiological_process
GO:0001974blood vessel remodelingIEAbiological_process
GO:0042472inner ear morphogenesisIEAbiological_process
GO:0030855epithelial cell differentiationIEAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0050679positive regulation of epithelial cell proliferatiIEAbiological_process
GO:0060425lung morphogenesisIEAbiological_process
GO:0006935chemotaxisIEAbiological_process
GO:0007368determination of left/right symmetryIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0071338positive regulation of hair follicle cell proliferIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0030538embryonic genitalia morphogenesisIEAbiological_process
GO:0050673epithelial cell proliferationIDAbiological_process
GO:0048514blood vessel morphogenesisIEAbiological_process
GO:0048536spleen developmentIEAbiological_process
GO:0010468regulation of gene expressionIEAbiological_process
GO:0035108limb morphogenesisIEAbiological_process
GO:0051145smooth muscle cell differentiationIEAbiological_process
GO:0043410positive regulation of MAPK cascadeIDAbiological_process
GO:0010631epithelial cell migrationIEAbiological_process
GO:0046877regulation of saliva secretionIMPbiological_process
GO:0048808male genitalia morphogenesisIEAbiological_process
GO:0060665regulation of branching involved in salivary glandIEAbiological_process
GO:0060430lung saccule developmentIMPbiological_process
GO:0042246tissue regenerationIEAbiological_process
GO:0061115lung proximal/distal axis specificationIEAbiological_process
GO:0008201heparin bindingIDAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0030949positive regulation of vascular endothelial growthIEAbiological_process
GO:0032808lacrimal gland developmentIEAbiological_process
GO:0005104fibroblast growth factor receptor bindingIDAmolecular_function
GO:0060615mammary gland bud formationIEAbiological_process
GO:0009986cell surfaceNAScellular_component
GO:0048146positive regulation of fibroblast proliferationIEAbiological_process
GO:0060054positive regulation of epithelial cell proliferatiNASbiological_process
GO:0060595fibroblast growth factor receptor signaling pathwaIEAbiological_process
GO:0050872white fat cell differentiationIEAbiological_process