Phosphorylation

Protein information

UniProt/SwissProt ID:	FCERB_HUMAN
Description:	membrane-spanning 4-domains, subfamily A, member 2 [Source:HGNC Symbol;Acc:7316]
Location:	chr11 q12.1
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
Y219	PEDRVyEELNI		PhosphoSitePlus; phosphoELM

FCERB_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000278888	M238T	COSMIC	Ovarian Cancer	21720365
ENSP00000278888	C74F	COSMIC	Head and Neck Cancer	21798893
ENSP00000278888	E119Q	COSMIC	Head and Neck Cancer	21798893
ENSP00000278888	M238T	TCGA	Ovarian Cancer	21720365, 18772890

FCERB_HUMAN is not differential expressed protein.

FCERB_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
LYN_HUMAN	FCERB_HUMAN	kinase -> substrate	KEGG

KEGG Pathway

KEGG ID	Pathway
hsa04664	Fc epsilon RI signaling pathway
hsa05310	Asthma

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0007205	protein kinase C-activating G-protein coupled rece	IEA	biological_process
GO:0006959	humoral immune response	TAS	biological_process
GO:0008283	cell proliferation	TAS	biological_process
GO:0019901	protein kinase binding	IEA	molecular_function
GO:0032998	Fc-epsilon receptor I complex	IEA	cellular_component
GO:0051279	regulation of release of sequestered calcium ion i	IEA	biological_process
GO:0043306	positive regulation of mast cell degranulation	IEA	biological_process
GO:0006954	inflammatory response	IEA	biological_process
GO:0005768	endosome	IEA	cellular_component
GO:0007165	signal transduction	IEA	biological_process
GO:0045121	membrane raft	IEA	cellular_component
GO:0042169	SH2 domain binding	IEA	molecular_function
GO:0070588	calcium ion transmembrane transport	TAS	biological_process
GO:0005887	integral to plasma membrane	IEA	cellular_component
GO:0016021	integral to membrane	IEA	cellular_component
GO:0009897	external side of plasma membrane	IEA	cellular_component
GO:0007166	cell surface receptor signaling pathway	IEA	biological_process
GO:0050663	cytokine secretion	IEA	biological_process
GO:0005262	calcium channel activity	TAS	molecular_function
GO:0019863	IgE binding	IEA	molecular_function
GO:0007202	activation of phospholipase C activity	IEA	biological_process
GO:0007186	G-protein coupled receptor signaling pathway	TAS	biological_process
GO:0051219	phosphoprotein binding	IEA	molecular_function

Human Phosphorylation Mediated
Signaling Transduction Network